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1.1.1.272: D-2-hydroxyacid dehydrogenase (NADP+)

This is an abbreviated version!
For detailed information about D-2-hydroxyacid dehydrogenase (NADP+), go to the full flat file.

Word Map on EC 1.1.1.272

Reaction

an (R)-2-hydroxycarboxylate
+
NADP+
=
a 2-oxocarboxylate
+
NADPH
+
H+

Synonyms

(R)-2-hydroxyacid dehydrogenase, (R)-sulfolactate dehydrogenase, (R)-sulfolactate:NAD(P)+ oxidoreductase, 2-D-hydroxyacid dehydrogenase, 2-HDH, 2HADH, D-2-hydroxyacid dehydrogenase, D-isomer specific 2-hydroxyacid dehydrogenase, D2-HDH, DDH, DDH_HALMT, HDH, L-2-hydroxyacid dehydrogenase, L-sulfolactate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.272 D-2-hydroxyacid dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.272 - D-2-hydroxyacid dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-dehydro-L-gulonic acid + NADPH + H+
L-idonate + NADP+
show the reaction diagram
2-oxo-3-methylvalerate + NADPH + H+
2-D-hydroxy-3-methylvalerate + NADP+
show the reaction diagram
2-oxo-4-methylpentanoate + NAD(P)H
(2R)-2-hydroxy-4-methylpentanoate + NAD(P)+
show the reaction diagram
2-oxobutyrate + NAD(P)H
(2R)-2-hydroxybutyrate + NAD(P)+
show the reaction diagram
2-oxobutyrate + NADH + H+
(2R)-2-hydroxybutyrate + NAD+
show the reaction diagram
-
-
-
r
2-oxobutyrate + NADPH + H+
2-D-hydroxybutyrate + NADP+
show the reaction diagram
-
-
-
r
2-oxoisocaproate + NADH + H+
2-D-hydroxyisocaproate + NAD+
show the reaction diagram
-
-
-
r
2-oxoisocaproate + NADPH + H+
2-hydroxyisocaproate + NADP+
show the reaction diagram
-
-
-
r
2-oxoisoleucine + NAD(P)H
2-D-hydroxyisoleucine + NAD(P)+
show the reaction diagram
2-oxoisoleucine + NADH + H+
2-D-hydroxyisoleucine + NAD+
show the reaction diagram
-
-
-
r
2-oxoisoleucine + NADPH + H+
2-D-hydroxyisoleucine + NADP+
show the reaction diagram
an (R)-2-hydroxycarboxylate + NADP+
a 2-oxocarboxylate + NADPH + H+
show the reaction diagram
pyruvate + NADPH + H+
D-lactate + NADP+
show the reaction diagram
additional information
?
-