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1.1.1.271: GDP-L-fucose synthase

This is an abbreviated version!
For detailed information about GDP-L-fucose synthase, go to the full flat file.

Word Map on EC 1.1.1.271

Reaction

GDP-beta-L-fucose
+
NADP+
=
GDP-4-dehydro-alpha-D-rhamnose
+
NADPH
+
H+

Synonyms

fcl, FX protein, GDP-4-keto-6-D-deoxymannose epimerase-reductase, GDP-4-keto-6-deoxy-D-mannose epimerase-reductase, GDP-4-keto-6-deoxy-D-mannose epimerase/reductase, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase, GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase/reductase, GDP-4-keto-6-deoxy-mannose-3,5-epimerase-4-reductase, GDP-4-keto-6-deoxymannose 3, 5-epimerase 4-reductase, GDP-4-keto-6-deoxymannose 3,5-epimerase 4-reductase, GDP-4-keto-6-deoxymannose 3,5-epimerase-4-reductase, GDP-4-keto-6-deoxymannose epimerase-reductase, GDP-4-keto-6-deoxymannose-3,5-epimerase-4-reductase, GDP-D-mannose-4,6-dehydratase, GDP-Fuc synthase, GDP-fucose synthase, GDP-fucose synthetase, GDP-fucose-synthesizing enzyme FX, GDP-keto-6-deoxymannose 3,5-epimerase/4-reductase, GDP-L-fucose synthetase, GDPFuc synthase, GER, GFS, GMER, guanosine diphosphofucose synthetase, P35B tumour rejection antigen, PF3D7_1014000, Red cell NADP(H)-binding protein, Transplantation antigen P35B, TSTA3, Tum-P35B antigen, wcaG

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.271 GDP-L-fucose synthase

Disease

Disease on EC 1.1.1.271 - GDP-L-fucose synthase

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DISEASE
TITLE OF PUBLICATION
LINK TO PUBMED
Breast Neoplasms
Oncogenic potential of TSTA3 in breast cancer and its regulation by the tumor suppressors miR-125a-5p and miR-125b.
Pathway-based classification of cancer subtypes.
Tissue-specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA-125a-5p in lung cancer.
Carcinogenesis
Oncogenic potential of TSTA3 in breast cancer and its regulation by the tumor suppressors miR-125a-5p and miR-125b.
Tissue-specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA-125a-5p in lung cancer.
Carcinoma
High TSTA3 Expression as a Candidate Biomarker for Poor Prognosis of Patients With ESCC.
Tissue-specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA-125a-5p in lung cancer.
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Carcinoma, Hepatocellular
An Alkynyl-Fucose Halts Hepatoma Cell Migration and Invasion by Inhibiting GDP-Fucose-Synthesizing Enzyme FX, TSTA3.
Expression of genes that control core fucosylation in hepatocellular carcinoma: Systematic review.
Tissue-specific transplantation antigen P35B (TSTA3) immune response-mediated metabolism coupling cell cycle to postreplication repair network in no-tumor hepatitis/cirrhotic tissues (HBV or HCV infection) by biocomputation.
Esophageal Squamous Cell Carcinoma
High TSTA3 Expression as a Candidate Biomarker for Poor Prognosis of Patients With ESCC.
Tissue-specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA-125a-5p in lung cancer.
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Insulin Resistance
Significant associations among hemostatic parameters, adipokines, and components of the metabolic syndrome in Japanese preschool children.
Lung Neoplasms
Tissue-specific transplantation antigen P35B functions as an oncogene and is regulated by microRNA-125a-5p in lung cancer.
Lymphatic Metastasis
High TSTA3 Expression as a Candidate Biomarker for Poor Prognosis of Patients With ESCC.
Multiple Sclerosis
GDP-l-fucose synthase is a CD4+ T cell-specific autoantigen in DRB3*02:02 patients with multiple sclerosis.
Neoplasm Metastasis
High TSTA3 Expression as a Candidate Biomarker for Poor Prognosis of Patients With ESCC.
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Neoplasms
Expression of genes that control core fucosylation in hepatocellular carcinoma: Systematic review.
Oncogenic potential of TSTA3 in breast cancer and its regulation by the tumor suppressors miR-125a-5p and miR-125b.
Pathway-based classification of cancer subtypes.
TSTA3 facilitates esophageal squamous cell carcinoma progression through regulating fucosylation of LAMP2 and ERBB2.
Osteonecrosis
ARG2, MAP4K5 and TSTA3 as Diagnostic Markers of Steroid-Induced Osteonecrosis of the Femoral Head and Their Correlation With Immune Infiltration.
Tuberculosis
Deciphering the genetic bases of the structural diversity of phenolic glycolipids in strains of the Mycobacterium tuberculosis complex.
Virus Diseases
Paramecium bursaria Chlorella virus 1 encodes two enzymes involved in the biosynthesis of GDP-L-fucose and GDP-D-rhamnose.