1.1.1.266: dTDP-4-dehydro-6-deoxyglucose reductase
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For detailed information about dTDP-4-dehydro-6-deoxyglucose reductase, go to the full flat file.
Reaction
Synonyms
dTDP-4-keto-6-deoxyglucose reductase
ECTree
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Systematic Name
Systematic Name on EC 1.1.1.266 - dTDP-4-dehydro-6-deoxyglucose reductase
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dTDP-alpha-D-fucopyranose:NAD(P)+ oxidoreductase
The enzymes from the Gram-negative bacteria Aggregatibacter actinomycetemcomitans and Escherichia coli O52 are involved in activation of fucose for incorporation into capsular polysaccharide O-antigens [1,3]. The enzyme from the Gram-positive bacterium Anoxybacillus tepidamans (Geobacillus tepidamans) is involved in activation of fucose for incorporation into the organism's S-layer [2]. The enzyme from Escherichia coli O52 has a higher catalytic efficiency with NADH than with NADPH [3].