1.1.1.26: glyoxylate reductase

This is an abbreviated version, for detailed information about glyoxylate reductase, go to the full flat file.

Reaction

glycolate
+
NAD+
=
glyoxylate
+
NADH
+
H+

Synonyms

GHPR, glycolate oxidase, glyoxylate reductase isoform 1, glyoxylate/hydroxypyruvate reductase, glyoxylic acid reductase, GLYR1, GLYR2, GxrA, NADH-dependent glyoxylate reductase, NADH-glyoxylate reductase, reductase, glyoxylate, SSO3187, succinic semialdehyde/glyoxylate reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.26 glyoxylate reductase

Reference

Reference on EC 1.1.1.26 - glyoxylate reductase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hullin, R.P.
Glyoxylate reductase, two forms from Pseudomonas
Methods Enzymol.
41B
343-348
1975
Pseudomonas fluorescens
Manually annotated by BRENDA team
Yokota, A.; Kitaoka, S.
Occurrence and subcellular distribution of enzymes involved in the glycolate pathways and their physiological function in a bleached mutant of Euglena gracilis Z.
Agric. Biol. Chem.
45
15-22
1981
Euglena gracilis
Manually annotated by BRENDA team
Suzuki, S.; Suga, T.; Ninobe, S.
Studies on peroxisomes. IV. intracellular localization of NADH2-glyoxylate reductase in rat liver
J. Biochem.
73
1033-1038
1973
Rattus norvegicus
Manually annotated by BRENDA team
Zelitch, I.
Glycolic acid oxidase and glyoxylic acid reductase
Methods Enzymol.
1
528-535
1955
Nicotiana tabacum, Spinacia oleracea
-
Manually annotated by BRENDA team
Zelitch, I.
The isolation and action of crystalline glyoxylic acid reductase from tobacco leaves
J. Biol. Chem.
216
553-575
1955
Nicotiana tabacum
Manually annotated by BRENDA team
Cerff, R.
Glyceraldehyde 3-phosphate dehydrogenases and glyoxylate reductase
Plant Physiol.
51
76-81
1973
Sinapis alba
Manually annotated by BRENDA team
Bergmeyer, H.U.; GraŻl, M.; Walter, H.E.
Glyoxylate reductase
Methods Enzym. Anal. , 3rd Ed. (Bergmeyer, H. U. , ed. )
2
126-328
1974
Spinacia oleracea
-
Manually annotated by BRENDA team
Zelitch, I.
Oxidation and reduction of glycolic and glyoxylic acids in plants II. glyoxylic acid reductase
J. Biol. Chem.
201
719-726
1953
Spinacia oleracea
Manually annotated by BRENDA team
Giafi, C.F.; Rumsby, G.
Kinetic analysis and tissue distribution of human D-glycerate dehydrogenase/glyoxylate reductase and its relevance to the diagnosis of primary hyperoxaluria type 2
Ann. Clin. Biochem.
35
104-109
1998
Homo sapiens
Manually annotated by BRENDA team
Rumsby, G.; Cregeen, D.P.
Identification and expression of a cDNA for human hydroxypyruvate/glyoxylate reductase
Biochim. Biophys. Acta
1446
383-388
1999
Homo sapiens
Manually annotated by BRENDA team
Givan, C.V.; Kleczkowski, L.A.
The enzymic reduction of glyoxylate and hydroxypyruvate in leaves of higher plants
Plant Physiol.
100
552-556
1992
Hordeum vulgare, Nicotiana tabacum, Petroselinum crispum, Pisum sativum, Spinacia oleracea, Zea mays
Manually annotated by BRENDA team
Betsche, T.; Schaller, D.; Melkonian, M.
Identification and characteriaztion of glycolate oxidase and related enzymes from the endocyanotic alga Cyanophora paradoxa and from pea leaves
Plant Physiol.
98
887-893
1992
Cyanophora paradoxa, Pisum sativum
Manually annotated by BRENDA team
Cregeen, D.P.; Williams, E.L.; Hulton, S.; Rumsby, G.
Molecular analysis of the glyoxylate reductase (GRHPR) gene and description of mutations underlying primary hyperoxaluria type 2
Hum. Mutat.
22
497
2003
Homo sapiens
Manually annotated by BRENDA team
Shinoda, T.; Arai, K.; Taguchi, H.
A highly specific glyoxylate reductase derived from a formate dehydrogenase
Biochem. Biophys. Res. Commun.
355
782-787
2007
Paracoccus sp.
Manually annotated by BRENDA team
Fauvart, M.; Braeken, K.; Daniels, R.; Vos, K.; Ndayizeye, M.; Noben, J.; Robben, J.; Vanderleyden, J.; Michiels, J.
Identification of a novel glyoxylate reductase supports phylogeny-based enzymatic substrate specificity prediction
Biochim. Biophys. Acta
1774
1092-1098
2007
Rhizobium etli, Rhizobium etli CFN42
Manually annotated by BRENDA team
Hoover, G.J.; Van Cauwenberghe, O.R.; Breitkreuz, K.E.; Clark, S.M.; Merrill, A.R.; Shelp, B.J.
Characteristics of an Arabidopsis glyoxylate reductase: general biochemical properties and substrate specificity for the recombinant protein, and developmental expression and implications for glyoxylate and succinic semialdehyde metabolism in planta
Can. J. Bot.
85
883-895
2007
Arabidopsis thaliana
Manually annotated by BRENDA team
Allan, W.L.; Clark, S.M.; Hoover, G.J.; Shelp, B.J.
Role of plant glyoxylate reductases during stress: a hypothesis
Biochem. J.
423
15-22
2009
Arabidopsis thaliana
Manually annotated by BRENDA team
Nunn, C.E.; Johnsen, U.; Schoenheit, P.; Fuhrer, T.; Sauer, U.; Hough, D.W.; Danson, M.J.
Metabolism of pentose sugars in the hyperthermophilic archaea Sulfolobus solfataricus and Sulfolobus acidocaldarius
J. Biol. Chem.
285
33701-33709
2010
Sulfolobus solfataricus (Q97U35), Sulfolobus solfataricus P2 (Q97U35)
Manually annotated by BRENDA team
Ching, S.L.; Gidda, S.K.; Rochon, A.; van Cauwenberghe, O.R.; Shelp, B.J.; Mullen, R.T.
Glyoxylate reductase isoform 1 is localized in the cytosol and not peroxisomes in plant cells
J. Integr. Plant Biol.
54
152-168
2012
Arabidopsis thaliana, Arabidopsis thaliana (Q9LSV0)
Manually annotated by BRENDA team
Ohshima, T.; Nunoura-Kominato, N.; Kudome, T.; Sakuraba, H.
A novel hyperthermophilic archaeal glyoxylate reductase from Thermococcus litoralis. Characterization, gene cloning, nucleotide sequence and expression in Escherichia coli
Eur. J. Biochem.
268
4740-4747
2001
Thermococcus litoralis (Q9C4M5), Thermococcus litoralis, Thermococcus litoralis DSM 5473 (Q9C4M5), Thermococcus litoralis DSM 5473
Manually annotated by BRENDA team