1.1.1.26: glyoxylate reductase

This is an abbreviated version, for detailed information about glyoxylate reductase, go to the full flat file.

Reaction

glycolate
+
NAD+
=
glyoxylate
+
NADH
+
H+

Synonyms

GHPR, glycolate oxidase, glyoxylate reductase isoform 1, glyoxylate/hydroxypyruvate reductase, glyoxylic acid reductase, GLYR1, GLYR2, GxrA, NADH-dependent glyoxylate reductase, NADH-glyoxylate reductase, reductase, glyoxylate, SSO3187, succinic semialdehyde/glyoxylate reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.26 glyoxylate reductase

Molecular Weight

Molecular Weight on EC 1.1.1.26 - glyoxylate reductase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
33000
-
4 * 33000, cytosolic enzyme
36500 - 40000
-
calculation from DNA sequence and non-denaturing PAGE
36807
2 * 36807, calculated from sequence
38000
-
2 * 38000, cytosolic enzyme with preference for hydroxypyruvate as substrate
38420
-
2 * 37000, recombinant His-tagged enzyme, SDS-PAGE, 2 * 38420, recombinant His-tagged enzyme, MALDI-TOF mass spectrometry
40000
-
1 * 40000, SDS-PAGE
70000
-
cytosolic enzyme with preference for hydroxypyruvate as substrate
76000
non-denaturimg gradient PAGE
77200
-
recombinant His-tagged enzyme, gel filtration
90000
-
peroxisomal enzyme with preference for hydroxypyruvate as substrate
125000
-
cytosolic enzyme
180000
-
thin-layer gel filtration