1.1.1.252: tetrahydroxynaphthalene reductase

This is an abbreviated version, for detailed information about tetrahydroxynaphthalene reductase, go to the full flat file.

Reaction

Scytalone
+
NADP+
=
1,3,6,8-Tetrahydroxynaphthalene
+
NADPH
+
H+

Synonyms

1,3,6,8-tetrahydroxynaphthalene reductase, 1,3,8-trihydroxynaphthalene reductase, 3HNR, 4HN, EC 1.3.1.50, hydroxynaphthalene reductase, NADPH-dependent naphthol reductase, naphthol reductase, reductase, naphthol, reductase, naphthol (Magnaporthe grisea clone pAV501 precursor reduced), T4HN reductase, T4HNR, tetrahydroxynaphthalene reductase (Magnaporthe grisea clone pAV501), THNR, trihydroxynaphthalene reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.252 tetrahydroxynaphthalene reductase

KI Value

KI Value on EC 1.1.1.252 - tetrahydroxynaphthalene reductase

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Ki VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.017
1H-indene-1,3(2H)-dione
-
pH 7.0
0.0026
5,7-dihydroxyflavone
-
-
0.01
7,4'-Dihydroxyflavone
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.0022
acacetin
-
-
0.0012
apigenin
-
-
0.0054
baicalein
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.0054
Biochanin A
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.0081
chrysoeriol
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.108
diclofenac
-
pH 7.0
0.0026
diosmetin
-
-
0.108
ethyl 6-methyl-4-oxo-4H-chromene-2-carboxylate
-
pH 7.0
0.111
ethyl 6-methyl-8-nitro-4-oxo-4H-chromene-2-carboxylate
-
pH 7.0
0.017
etodolac
-
pH 7.0
0.025
flavone
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.0036
kaempferol
-
-
0.0031
luteolin
-
-
0.111
nabumetone
-
pH 7.0
0.012
naringenin
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.012
quercetin
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C
0.0068
scutellarein
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25°C