1.1.1.252: tetrahydroxynaphthalene reductase

This is an abbreviated version, for detailed information about tetrahydroxynaphthalene reductase, go to the full flat file.

Reaction

Scytalone
+
NADP+
=
1,3,6,8-Tetrahydroxynaphthalene
+
NADPH
+
H+

Synonyms

1,3,6,8-tetrahydroxynaphthalene reductase, 1,3,8-trihydroxynaphthalene reductase, 3HNR, 4HN, EC 1.3.1.50, hydroxynaphthalene reductase, NADPH-dependent naphthol reductase, naphthol reductase, reductase, naphthol, reductase, naphthol (Magnaporthe grisea clone pAV501 precursor reduced), T4HN reductase, T4HNR, tetrahydroxynaphthalene reductase (Magnaporthe grisea clone pAV501), THNR, trihydroxynaphthalene reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.252 tetrahydroxynaphthalene reductase

IC50 Value

IC50 Value on EC 1.1.1.252 - tetrahydroxynaphthalene reductase

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IC50 VALUE [mM]
INHIBITOR
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.025
3,7-dihydroxyflavone
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one
0.025
3-hydroxyflavone
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one
0.0058
5,7-dihydroxyflavone
0.025
5-hydroxyflavone
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one
0.025
5-methoxyflavone
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one
0.023
7,4'-Dihydroxyflavone
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.0049
acacetin
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.0031
apigenin
0.012
baicalein
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.012
Biochanin A
0.018
chrysoeriol
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.0057
diosmetin
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.055
flavone
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.0079
kaempferol
0.0068
luteolin
0.026
naringenin
0.026
quercetin
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C
0.015
scutellarein
Curvularia lunata
-
at 0.04 mM 2,3-dihydro-2,5-dihydroxy-4H-benzopyran-4-one, at pH 7.0 and 25C