1.1.1.25: shikimate dehydrogenase

This is an abbreviated version, for detailed information about shikimate dehydrogenase, go to the full flat file.

Reaction

shikimate
+
NADP+
=
3-dehydroshikimate
+
NADPH
+
H+

Synonyms

3-dehydroquinate dehydratase/shikimate dehydrogenase, 5-dehydroshikimate reductase, ael1, Af2327, AroE, cgR_0495, cgR_1677, dehydroquinate dehydratase-shikimate dehydrogenase, dehydroshikimic reductase, DHD/SHD, DHQ-SDH, HI0607, More, MtbSD, NADP-dependent shikimate dehydrogenase, qsuD, rifI, SD, SDH, sdhL, shikimate 5-dehydrogenase, shikimate dehydrogenase, shikimate oxidoreductase, shikimate:NADP oxidoreductase, shikimate:NADP+ 5-oxidoreductase, SKDH, tm0346

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.25 shikimate dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.25 - shikimate dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
0
-
oxidation of shikimate
6
reduction of 3-dehydroquinate
6.8 - 7.2
formation of shikimate
7.5
-
assay at
7.5 - 9.8
-
paralogue HI0607
7.7
-
Tris-HCl acid buffer
8 - 9
oxidation reaction, recombinant His-tagged enzyme
8.8
assay at; assay at; assay at; assay at
9 - 9.4
formation of 3-dehydroshikimate
9
assay at; assay at
10.1
-
glycine-sodium hydroxide buffer