1.1.1.245: cyclohexanol dehydrogenase

This is an abbreviated version, for detailed information about cyclohexanol dehydrogenase, go to the full flat file.

Reaction

Cyclohexanol
+
NAD+
=
cyclohexanone
+
NADH
+
H+

Synonyms

alcohol dehydrogenase, cyclohexanol dehydrogenase II, dehydrogenase, cyclohexanol, SSADH

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.245 cyclohexanol dehydrogenase

KM Value

KM Value on EC 1.1.1.245 - cyclohexanol dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.41
Cyclohexane-1,2-diol
-
pH 10.3
0.5
Cyclohexane-1,3-diol
-
pH 10.3
0.59
Cyclohexane-1,4-diol
-
pH 10.3
0.0013 - 0.05
Cyclohexanol
0.0142
Cyclopentanol
-
isoenzyme II at pH 7.6
0.0135
hexane-1,2-diol
-
isoenzyme II at pH 7.6
0.024 - 0.04
NAD+
0.0028
trans-Cyclohexane-1,2-diol
-
isoenzyme II at pH 7.6
0.0137
trans-cyclopentane-1,2-diol
-
isoenzyme II at pH 7.6
additional information
additional information
-
steady-state kinetic measurements show that SsADH displays standard Michaelis–Menten kinetics between 35°C and 45°C, but exhibits positive and negative cooperativity for NADH oxidation below and above this range of temperatures, respectively
-