1.1.1.244: methanol dehydrogenase

This is an abbreviated version, for detailed information about methanol dehydrogenase, go to the full flat file.

Reaction

methanol
+
NAD+
=
formaldehyde
+
NADH
+
H+

Synonyms

activator-independent methanol dehydrogenase, ADH, BFZC1_05383, BsMdh, Bsph_4187, CNE_2c13570, dehydrogenase, methanol, EC 1.1.99.8, group III NAD-dependent alcohol dehydrogenase, MDH, Mdh1, MDH2, Mdh3, MEDH, More, mxaF, NAD+ dependent methanol dehydrogenase, NAD-dependent MDH, NAD-dependent methanol dehydrogenase, XoxF

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.244 methanol dehydrogenase

Temperature Stability

Temperature Stability on EC 1.1.1.244 - methanol dehydrogenase

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
30 - 60
purified recombinant His-tagged enzyme, 10 min, pH 9.5, stable up to 30°C, inactivation above, 13 % of activity remains after preincubation at 55°C and the activity is abolished at 60°C
45
-
20 min, the isozymes are all stable up to; 20 min, the isozymes are stable up to, except for isozyme Mdh1, which shows about 35-40% loss of activity
50
-
t1/2: above 2 min
70
-
t1/2: 2 min