1.1.1.238: 12beta-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 12beta-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

3alpha,7alpha,12beta-trihydroxy-5beta-cholan-24-oate
+
NADP+
=
3alpha,7alpha-dihydroxy-12-oxo-5beta-cholan-24-oate
+
NADPH
+
H+

Synonyms

12beta-hydroxy steroid (nicotinamide adenine dinucleotide phosphate) dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.238 12beta-hydroxysteroid dehydrogenase

Reference

Reference on EC 1.1.1.238 - 12beta-hydroxysteroid dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Edenharder, R.; Pfutzner, A.
Characterization of NADP-dependent 12beta-hydroxysteroid dehydrogenase from Clostridium paraputrificum
Biochim. Biophys. Acta
962
362-370
1988
Clostridium paraputrificum
Manually annotated by BRENDA team