1.1.1.237: hydroxyphenylpyruvate reductase

This is an abbreviated version, for detailed information about hydroxyphenylpyruvate reductase, go to the full flat file.

Reaction

3-(4-hydroxyphenyl)lactate
+
NAD+
=
3-(4-hydroxyphenyl)pyruvate
+
NADH
+
H+

Synonyms

4-hydroxyphenylpyruvate reductase, H(P)PR, HPPR, HPRP, hydroxy(phenyl)pyruvate reductase, hydroxyphenylpyruvate reductase, hydroxyphenylpyruvic acid reductase, Ppr, pprA

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.237 hydroxyphenylpyruvate reductase

Inhibitors

Inhibitors on EC 1.1.1.237 - hydroxyphenylpyruvate reductase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
4-hydroxyphenylpyruvate
-
substrate inhibition
Cu2+
1 mM, less than 10% residual activity
dihydroxyphenylpyruvate
-
substrate inhibition
Fe2+
1 mM, less than 10% residual activity
Hg2+
1 mM, less than 10% residual activity
oxaloacetate
-
inhibition at 5 mM
p-Coumaroyl-CoA
pyruvate
rosmarinic acid
WO42-
1 mM, less than 10% residual activity
Zn2+
1 mM, less than 10% residual activity