1.1.1.234: flavanone 4-reductase

This is an abbreviated version, for detailed information about flavanone 4-reductase, go to the full flat file.

Reaction

(2S)-Flavan-4-ol
+
NADP+
=
(2S)-flavanone
+
NADPH
+
H+

Synonyms

3-deoxyanthocyanidin synthase, FNR, Sb06g029550, Sb06g029550 protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.234 flavanone 4-reductase

General Information

General Information on EC 1.1.1.234 - flavanone 4-reductase

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GENERAL INFORMATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
evolution
the enzyme belongs to the plant DFR superfamily, phylogenetic analysis
malfunction
Sorghums with a tan injury response have non-functional FNR alleles (p). The FNR gene of cultivar M36001 has an insertion in the coding region. Sorghums with a tan injury response have lower levels of flavan-4-ols (precursors of apigeninidin and luteolinidin-apiforol and luteoforol, respectively) than do sorghums with a purple or red injury response and are unable to synthesize 3-deoxyanthocyanidins
metabolism
physiological function
additional information
homology modeling on the basis of the crystal structure of grape dihydroflavonol 4-reductase, PDB ID 3C1T