1.1.1.22: UDP-glucose 6-dehydrogenase

This is an abbreviated version, for detailed information about UDP-glucose 6-dehydrogenase, go to the full flat file.

Reaction

UDP-alpha-D-glucose
+ 2 NAD+ +
H2O
=
UDP-alpha-D-glucuronate
+ 2 NADH + 2 H+

Synonyms

ADH-like UDP-glucose dehydrogenase, AglM, BceC, dehydrogenase, uridine diphosphoglucose, dual specificity UDP-glucose dehydrogenase, HasB, HasB2, HVO_1531, PA2022, PA3559, sqv-4, Sugarless protein, UDP-alpha-D-glucose:NAD oxidoreductase, UDP-D-glucose dehydrogenase, UDP-GDH, UDP-Glc dehydrogenase, UDP-Glc DH, UDP-GlcDH, UDP-GlcDHase, UDP-glucose dehydrogenase, UDPDH, UDPG dehydrogenase, UDPG-DH, UDPG:NAD oxidoreductase, UDPGD, UDPGDH, UDPGDH-A, UDPGDH-B, UDPGlc dehydrogenase, UDPglucose dehydrogenase, UDPglucose:NAD+ oxidoreductase, Ugd, UGD1, UgdG, UGDH, uridine diphosphate D-glucose dehydrogenase, uridine diphosphate glucose dehydrogenase, uridine diphosphate glucose-6-dehydrogenase, uridine diphosphate-glucose dehydrogenase, uridine diphosphoglucose dehydrogenase, uridine-5'-diphosphoglucose dehydrogenase, uridyl phosphate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.22 UDP-glucose 6-dehydrogenase

Molecular Weight

Molecular Weight on EC 1.1.1.22 - UDP-glucose 6-dehydrogenase

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
40000
-
? * 40000, SDS-PAGE
42000
x * 42000, SDS-PAGE, x * 43400, calculated
43000
x * 43000, SDS-PAGE
43400
x * 42000, SDS-PAGE, x * 43400, calculated
45500
-
electrospray mass spectrometry
47000
-
2 * 47000, SDS-PAGE
48500
-
x * 48500, SDS-PAGE and calculated for His-tagged protein
52600
-
x * 52600, recombinant His6-tagged BceC, SDS-PAGE
53100
x * 53100, deduced from gene sequence
54500
54500, calculated
55000
-
gel filtration
56300
x * 56300, calculated, x * 60000, SDS-PAGE
57400
57400, calculated
60000
x * 56300, calculated, x * 60000, SDS-PAGE
70000
-
4 * 70000, gel filtration after treatment with SDS
72000
-
gel filtration
86000
-
gel filtration
104000
gel filtration
110000
-
gel filtration, minor part of wild-type, mutant A222Q/S233G
117000
gel filtration
300000
305000
-
equilibrium measurement under native conditions
340000
345000
gel filtration, dynamic light scattering