UDP-glucose 6-dehydrogenase

This is an abbreviated version, for detailed information about UDP-glucose 6-dehydrogenase, go to the full flat file.


+ 2 NAD+ +
+ 2 NADH + 2 H+


ADH-like UDP-glucose dehydrogenase, AglM, BceC, dehydrogenase, uridine diphosphoglucose, dual specificity UDP-glucose dehydrogenase, GbUGD, HasB, HasB2, HVO_1531, PA2022, PA3559, sqv-4, Sugarless protein, UDG1, UDP-alpha-D-glucose:NAD oxidoreductase, UDP-D-glucose dehydrogenase, UDP-GDH, UDP-Glc dehydrogenase, UDP-Glc DH, UDP-GlcDH, UDP-GlcDHase, UDP-glucose dehydrogenase, UDPDH, UDPG dehydrogenase, UDPG-DH, UDPG:NAD oxidoreductase, UDPGD, UDPGDH, UDPGDH-A, UDPGDH-B, UDPGlc dehydrogenase, UDPglucose dehydrogenase, UDPglucose:NAD+ oxidoreductase, Ugd, UGD1, UgdG, UGDH, uridine diphosphate D-glucose dehydrogenase, uridine diphosphate glucose dehydrogenase, uridine diphosphate glucose-6-dehydrogenase, uridine diphosphate-glucose dehydrogenase, uridine diphosphoglucose dehydrogenase, uridine-5'-diphosphoglucose dehydrogenase, uridyl phosphate dehydrogenase, VNG1048G, VNG_1048G


     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
       UDP-glucose 6-dehydrogenase


Expression on EC - UDP-glucose 6-dehydrogenase

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dihydrotestosterone increases UGDH expression 2.5fold in androgen-dependent cells. However, upregulation of UGDH does not affect hyaluronan synthase expression or enhance hyaluronan production
expression of Ugd is induced by polymyxin B through RppA, a putative response regulator of the bacterial two-component system
interleukin-1beta, IL-1beta, suppresses UGDH gene expression in human articular chondrocytes in the late phase, which also modulates gene expression of Sp1, Sp3 and c-Krox and increased both Sp3/Sp1 and c-Krox/Sp1 ratio. The inhibition of SAP/JNK and p38 MAPK pathways both result in an obvious attenuation of the IL-1beta-induced suppression on UGDH gene expression