1.1.1.218: morphine 6-dehydrogenase

This is an abbreviated version, for detailed information about morphine 6-dehydrogenase, go to the full flat file.

Reaction

morphine
+
NAD(P)+
=
morphinone
+
NAD(P)H
+
H+

Synonyms

AKR1C34, M6DH, More, morphine 6-dehydrogenase, morphine-6-dehydrogenase, naloxone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.218 morphine 6-dehydrogenase

Cloned

Cloned on EC 1.1.1.218 - morphine 6-dehydrogenase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
gene AKR1C26, DNA and amino acid sequence determination and analysis, sequence comparisons, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)pLysS
gene AKR1C34, cloned from liver, DNA and amino acid sequence determination and analysis, sequence comparisons, recombinant expression of His-tagged enzyme in Escherichia coli strain BL21(DE3)pLysS
gene encoding morphine dehydrogenase on natural plasmid, expressed in Escherichia coli
-
plasmid containing the gene for morphine dehydrogenase: pMDH1.7
-