1.1.1.214: 2-dehydropantolactone reductase (Si-specific)

This is an abbreviated version, for detailed information about 2-dehydropantolactone reductase (Si-specific), go to the full flat file.

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

2-dehydropantoyl-lactone reductase (B-specific), 2-ketopantoyl lactone reductase, 2-oxopantoyl lactone reductase, CPR-C1, CPR-C2, ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.214 2-dehydropantolactone reductase (Si-specific)

Substrates Products

Substrates Products on EC 1.1.1.214 - 2-dehydropantolactone reductase (Si-specific)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(R)-pantolactone + NADP+
2-dehydropantolactone + NADPH
show the reaction diagram
acenaphthenequinone
?
show the reaction diagram
-
-
-
?
bornanedione + NADPH
?
show the reaction diagram
-
-
-
?
isatin + NADPH
?
show the reaction diagram
-
-
-
?
keto-omega-methylpantoyl lactone + NADPH
methylpantoyl lactone + NADP+
show the reaction diagram
-
the only compound other than ketopantoyl lactone which is a substrate, 73% relative activity to ketopantoyl lactone with form A enzyme, 56% relative activity to ketopantoyl lactone with form B enzyme
-
?
ketopantoyl lactone + NADPH
pantoyl lactone + NADP+
show the reaction diagram
additional information
?
-