1.1.1.214: 2-dehydropantolactone reductase (Si-specific)

This is an abbreviated version, for detailed information about 2-dehydropantolactone reductase (Si-specific), go to the full flat file.

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

2-dehydropantoyl-lactone reductase (B-specific), 2-ketopantoyl lactone reductase, 2-oxopantoyl lactone reductase, CPR-C1, CPR-C2, ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.214 2-dehydropantolactone reductase (Si-specific)

Reference

Reference on EC 1.1.1.214 - 2-dehydropantolactone reductase (Si-specific)

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Wilken, D.R.; King, H.L.; Dyar, R.E.
Ketopantoic acid and ketopantoyl lactone reductases. Stereospecificity of transfer of hydrogen from reduced nicotinamide adenine dinucleotide phosphate
J. Biol. Chem.
250
2311-2314
1975
Escherichia coli
Manually annotated by BRENDA team
Julliard, J.H.
Purification and characterization of oxopantoyl lactone reductase from higher plants: role in pantothenate synthesis
Bot. Acta
107
191-200
1994
Spinacia oleracea
-
Manually annotated by BRENDA team
Kataoka, M.; Delacruz-Hidalgo, A.R.G.; Akond, M.A.; Sakuradani, E.; Kita, K.; Shimizu, S.
Gene cloning and overexpression of two conjugated polyketone reductases, novel aldo-keto reductase family enzymes, of Candida parapsilosis. Investigation of hydroxamic acids as laccase-mediators for pulp bleaching
Appl. Microbiol. Biotechnol.
64
359-366
2004
Candida parapsilosis, Candida parapsilosis (Q76L36), Candida parapsilosis (Q76L37), Candida parapsilosis IFO 0708, Candida parapsilosis IFO 0708 (Q76L36), Candida parapsilosis IFO 0708 (Q76L37)
Manually annotated by BRENDA team