Any feedback?
Please rate this page
(all_enzymes.php)
(0/150)

BRENDA support

1.1.1.214: 2-dehydropantolactone reductase (Si-specific)

This is an abbreviated version!
For detailed information about 2-dehydropantolactone reductase (Si-specific), go to the full flat file.

Word Map on EC 1.1.1.214

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

2-dehydropantoyl-lactone reductase (B-specific), 2-ketopantoyl lactone reductase, 2-oxopantoyl lactone reductase, conjugated polyketone reductase, conjugated polyketone reductase C2, CORT_0G03830, CPR, CPR-C1, CPR-C2, ketopantoyl lactone reductase, NADPH-dependent conjugated polyketone reductase, NADPH-dependent ketopantoyl lactone reductase, nicotinamide adenine dinucleotide phosphate-dependent ketopantoyl lactone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.214 2-dehydropantolactone reductase (Si-specific)

Natural Substrates Products

Natural Substrates Products on EC 1.1.1.214 - 2-dehydropantolactone reductase (Si-specific)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
NATURAL SUBSTRATE
NATURAL PRODUCT
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
REVERSIBILITY
r=reversible
ir=irreversible
?=not specified
(R)-pantolactone + NADP+
2-dehydropantolactone + NADPH
show the reaction diagram
(R)-pantolactone + NADP+
2-dehydropantolactone + NADPH + H+
show the reaction diagram
2-dehydropantolactone + NADPH + H+
(R)-pantolactone + NADP+
show the reaction diagram
ketopantoyl lactone + NADPH
pantoyl lactone + NADP+
show the reaction diagram
-
-
the enzyme is involved in pantothenate biosynthesis, pantoyl lactone, the putative product of the reaction, together with beta-alanine and ATP are the substrate of pantothenate synthase
?
additional information
?
-
-
the physiological substrate for the enzyme is uncertain, the physiological function of the enzyme is unknown
-
-
?