1.1.1.210: 3beta(or 20alpha)-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 3beta(or 20alpha)-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

5alpha-androstan-3beta,17beta-diol
+
NADP+
=
17beta-hydroxy-5alpha-androstan-3-one
+
NADPH
+
H+

Synonyms

3beta,20alpha-hydroxysteroid oxidoreductase, dehydrogenase, 3beta,20alpha-hydroxy steroid, progesterone reductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.210 3beta(or 20alpha)-hydroxysteroid dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.210 - 3beta(or 20alpha)-hydroxysteroid dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
17beta-hydoxy-5alpha-androstan-3-one + NADPH
5alpha-androstan-3beta,17beta-diol + NADP+
show the reaction diagram
17beta-hydroxy-5alpha-androstan-3-one + NADPH
5alpha-androstan-3beta,17beta-diol + NADP+
show the reaction diagram
progesterone + NADPH
20alpha-hydroxy-4-pregnen-3-one + NADP+
show the reaction diagram
additional information
?
-
-
enzyme is involved in progesterone biosynthesis
-
-
-