1.1.1.207: (-)-menthol dehydrogenase

This is an abbreviated version, for detailed information about (-)-menthol dehydrogenase, go to the full flat file.

Reaction

(-)-menthol
+
NADP+
=
(-)-menthone
+
NADPH
+
H+

Synonyms

(-)-menthone:(3R)-menthol reductase, dehydrogenase, menthol, menthone:(-)-menthol reductase, MMR, monoterpenoid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.207 (-)-menthol dehydrogenase

Application

Application on EC 1.1.1.207 - (-)-menthol dehydrogenase

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APPLICATION
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
agriculture
-
transcript level of menthol dehydrogenase/menthone reductase is highly upregulated in plants treated with calliterpenone, leading to increased content of menthone and menthol in oil
synthesis
the enzyme is useful, together with menthone:(+)-neomenthol reductase (EC 1.1.1.208), for production of (1R,2S,5R)-(-)-menthol and (1S,2S,5R)-(+)-neomenthol from pulegone, development of a one-pot synthesis method, overview. Menthol isomers, (1R,2S,5R)-(-)-menthol, (1R,2S,5S)-(+)-isomenthol, (1S,2S,5R)-(+)-neomenthol, and (1R,2R,5R)-(+)-neoisomenthol, and carvone are used as additives in oral hygiene products and flavors in food and beverages, or cosmetics