1.1.1.206: tropinone reductase I

This is an abbreviated version, for detailed information about tropinone reductase I, go to the full flat file.

Reaction

Tropine
+
NADP+
=
tropinone
+
NADPH
+
H+

Synonyms

BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, More, TR-I, TR1, TRI, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, WcTR-I, WsTR-I, WsTR-I protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.206 tropinone reductase I

KM Value

KM Value on EC 1.1.1.206 - tropinone reductase I

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.004 - 2.11
3-methylcyclohexanone
0.167 - 5.17
3-quinuclidinone
0.003
4-ethylcyclohexanone
-
-
0.001 - 8.71
4-methylcyclohexanone
0.003
8-thiabicyclo(3,2,1)octane-3-one
-
-
0.231
N-Methyl-4-piperidone
-
-
1.74
N-methylpiperidine
recombinant enzyme, pH 6.7, 30C
10
NADH
-
-
0.013 - 0.208
NADP+
0.00043 - 0.127
NADPH
0.073 - 2
nortropine
3.03
Nortropinone
-
-
0.91
Scopine
-
-
0.006 - 114.9
Tropine
0.775 - 5.61
tropinone
additional information
additional information
-