1.1.1.206: tropinone reductase I

This is an abbreviated version, for detailed information about tropinone reductase I, go to the full flat file.

Reaction

Tropine
+
NADP+
=
tropinone
+
NADPH
+
H+

Synonyms

BaTRI, dehydrogenase, tropine, DnTR1, DsTRI, More, TR-I, TR1, TRI, tropine biosynthetic tropinone reductase, Tropine dehydrogenase, tropine-forming reductase, tropine-forming tropinone reductase, tropinone reductase, tropinone reductase I, tropinone reductase II, tropinone reductase-I, WcTR-I, WsTR-I, WsTR-I protein

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.206 tropinone reductase I

KCat KM Value

KCat KM Value on EC 1.1.1.206 - tropinone reductase I

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kcat/KM VALUE [1/mMs-1]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5.17
3-methylcyclohexanone
recombinant enzyme, pH 6.7, 30C
0.1045 - 22.18
3-quinuclidinone
0.0032 - 10.15
4-methylcyclohexanone
4.38
N-methylpiperidine
recombinant enzyme, pH 6.7, 30C
0.559 - 14
NADP+
53 - 77540
NADPH
0.014 - 10.16
Tropine
0.00094 - 11.53
tropinone