1.1.1.202: 1,3-propanediol dehydrogenase

This is an abbreviated version, for detailed information about 1,3-propanediol dehydrogenase, go to the full flat file.

Reaction

Propane-1,3-diol
+
NAD+
=
3-hydroxypropanal
+
NADH
+
H+

Synonyms

(NADH)-linked 1,3-PD oxidoreductase, 1,3-PD dehydrogenase, 1,3-PD oxidoreductase, 1,3-PD-DH, 1,3-PD:NAD+ oxidoreductase, 1,3-Pdiol dehydrogenase, 1,3-propanediol dehydrogenase, 1,3-propanediol oxidoreductase, 1,3-propanediol-oxidoreductase, 1,3-propanediol:NAD oxidoreductase, 3-hydroxypropionaldehyde reductase, ADH3, dehydrogenase, 1,3-propanediol, DhaT, lr_0030, lr_1734, NADH-linked 1,3-propanediol oxidoreductase, PDOR, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.202 1,3-propanediol dehydrogenase

Reference

Reference on EC 1.1.1.202 - 1,3-propanediol dehydrogenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Johnson, E.A.; Lin, E.C.C.
Klebsiella pneumoniae 1,3-propanediol:NAD+ oxidoreductase
J. Bacteriol.
169
2050-2054
1987
Klebsiella pneumoniae
Manually annotated by BRENDA team
Heyndrickx, M.; De Vos, P.; Vancanneyt, M.; De Ley, J.
The fermentation of glycerol by Clostridium butyricum LMG 1212t2 and 1213t1 and C. pasteurianum LMG 3285
Appl. Microbiol. Biotechnol.
34
637-642
1991
Clostridium butyricum, Clostridium butyricum LMG 1212t2, Clostridium pasteurianum, Clostridium pasteurianum LMG 3285
-
Manually annotated by BRENDA team
Talarico, T.L.; Axelsson, L.T.; Novotny, J.; Fiuzat, M.; Dobrogosz, W.J.
Utilization of glycerol as a hydrogen acceptor by Lactobacillus reuteri: purification of 1,3-propanediol:NAD+ oxidoreductase
Appl. Environ. Microbiol.
56
943-948
1990
Lactobacillus reuteri
Manually annotated by BRENDA team
Abeles, R.H.; Brownstein, A.M.; Randles, C.H.
beta-Hydroxypropionaldehyde, an intermediate in the formation of 1,3-propanediol by Aerobacter aerogenes
Biochim. Biophys. Acta
41
530-531
1960
Klebsiella pneumoniae
Manually annotated by BRENDA team
Schutz, H.; Radler, F.
Anaerobic reduction of glycerol to propanediol-1,3 by Lactobacillus brevis and Lactobacillus buchneri
Syst. Appl. Microbiol.
5
169-178
1984
Lactobacillus brevis, Lactobacillus buchneri
-
Manually annotated by BRENDA team
Sprenger, G.A.; Hammer, B.A.; Johnson, E.A.; Lin, E.C.C.
Anaerobic growth of Escherichia coli on glycerol by importing genes of the dha regulon from Klebsiella pneumoniae
J. Gen. Microbiol.
135
1255-1262
1989
Klebsiella pneumoniae
Manually annotated by BRENDA team
Daniel, R.; Boenigk, R.; Gottschalk, G.
Purification of 1,3-propanediol dehydrogenase from Citrobacter freundii and cloning, sequencing, and overexpression of the corresponding gene in Escherichia coli
J. Bacteriol.
177
2151-2156
1995
Citrobacter freundii
Manually annotated by BRENDA team
Luers, F.; Seyfried, M.; Daniel, R.; Gottschalk, G.
Glycerol conversion to 1,3-propanediol by Clostridium pasteurianum: cloning and expression of the gene encoding 1,3-propanediol dehydrogenase
FEMS Microbiol. Lett.
154
337-345
1997
Clostridium pasteurianum
Manually annotated by BRENDA team
Malaoui, H.; Marczak, R.
Purification and characterization of the 1,3-propanediol dehydrogenase of Clostridium butyricum E5
Enzyme Microb. Technol.
27
399-405
2000
Clostridium butyricum, Clostridium butyricum E5
Manually annotated by BRENDA team
Abbad-Andaloussi, S.; Amine, J.; Gerard, P.; Petitdemange, H.
Effect of glucose on glycerol metabolism by Clostridium butyricum DSM 5431
J. Appl. Microbiol.
84
515-522
1998
Clostridium butyricum
Manually annotated by BRENDA team
Veiga-da-Cunha, M.; Foster, M.A.
1,3-Propanediol:NAD+ oxidoreductases of Lactobacillus brevis and Lactobacillus buchneri
Appl. Environ. Microbiol.
58
2005-2010
1992
Lactobacillus brevis, Lactobacillus buchneri
Manually annotated by BRENDA team
Zheng, Y.; Yang, C.; Baishan, F.
Cloning and sequence analysis of the dhaT gene of the 1,3-propanediol regulon from Klebsiella pneumoniae
Biotechnol. Lett.
26
251-255
2004
Klebsiella pneumoniae, Klebsiella pneumoniae (Q7WRJ3)
Manually annotated by BRENDA team
Schwarzenbacher, R.; von Delft, F.; Canaves, J.M.; Brinen, L.S.; Dai, X.; Deacon, A.M.; Elsliger, M.A.; Eshaghi, S.; Floyd, R.; Godzik, A.; Grittini, C.; Grzechnik, S.K.; Guda, C.; Jaroszewski, L.; Karlak, C.; Klock, H.E.; Koesema, E.; Kovarik, J.S.; Kreusch, A.; Kuhn, P.; Lesley, S.A.; McMullan, D.; McPhillips, T.M.; Miller, M.A.; Miller, M.D.; Morse, A.; Moy, K.; Ouyang, J.; Page, R.; Robb, A.; Rodrigues, K.; Selby, T.L.; Spraggon, G.; Stevens, R.C.; van den Bedem, H.; Velasquez, J.; Vincent, J.; Wang, X.; West, B.; Wolf, G.; Hodgson, K.O.; Wooley, J.; Wilson, I.A.
Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution
Proteins
54
174-177
2003
Thermotoga maritima (Q9X022), Thermotoga maritima
Manually annotated by BRENDA team
Nemeth, A.; Kupcsulik, B.; Sevella, B.
1,3-Propanediol oxidoreductase production with Klebsiella pneumoniae DSM2026
World J. Microbiol. Biotechnol.
19
659-663
2003
Klebsiella pneumoniae, Klebsiella pneumoniae DSM 2026
-
Manually annotated by BRENDA team
Lin, R.; Liu, H.; Hao, J.; Cheng, K.; Liu, D.
Enhancement of 1,3-propanediol production by Klebsiella pneumoniae with fumarate addition
Biotechnol. Lett.
27
1755-1759
2005
Klebsiella pneumoniae, Klebsiella pneumoniae M5a1
Manually annotated by BRENDA team
Gonzalez-Pajuelo, M.; Meynial-Salles, I.; Mendes, F.; Soucaille, P.; Vasconcelos, I.
Microbial conversion of glycerol to 1,3-propanediol: physiological comparison of a natural producer, Clostridium butyricum VPI 3266, and an engineered strain, Clostridium acetobutylicum DG1(pSPD5)
Appl. Environ. Microbiol.
72
96-101
2006
Clostridium butyricum, Clostridium butyricum VPI 3266
Manually annotated by BRENDA team
Fenghuan, W.; Huijin, Q.; He, H.; Tan, T.
High-level expression of the 1,3-propanediol oxidoreductase from Klebsiella pneumoniae in Escherichia coli
Mol. Biotechnol.
31
211-219
2005
Klebsiella pneumoniae
Manually annotated by BRENDA team
Wang, F.; Qu, H.; Zhang, D.; Tian, P.; Tan, T.
Production of 1,3-propanediol from glycerol by recombinant E. coli using incompatible plasmids system
Mol. Biotechnol.
37
112-119
2007
Klebsiella pneumoniae
Manually annotated by BRENDA team
Marcal, D.; Rego, A.T.; Fogg, M.J.; Wilson, K.S.; Carrondo, M.A.; Enguita, F.J.
Crystallization and preliminary X-ray characterization of 1,3-propanediol dehydrogenase from the human pathogen Klebsiella pneumoniae
Acta Crystallogr. Sect. F
63
249-251
2007
Klebsiella pneumoniae
Manually annotated by BRENDA team
Nemeth, A.; Sevella, B.
Development of a new bioprocess for production of 1,3-propanediol I.: modeling of glycerol bioconversion to 1,3-propanediol with Klebsiella pneumoniae enzymes
Appl. Biochem. Biotechnol.
144
47-58
2008
Klebsiella pneumoniae
Manually annotated by BRENDA team
Hao, J.; Wang, W.; Tian, J.; Li, J.; Liu, D.
Decrease of 3-hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae TUAC01
J. Ind. Microbiol. Biotechnol.
35
735-741
2008
Klebsiella pneumoniae (A3RL85), Klebsiella pneumoniae, Klebsiella pneumoniae TUAC01 (A3RL85), Klebsiella pneumoniae TUAC01
Manually annotated by BRENDA team
Ma, Z.; Rao, Z.; Zhuge, B.; Fang, H.; Liao, X.; Zhuge, J.
Construction of a Novel Expression System in Klebsiella pneumoniae and its Application for 1,3-Propanediol Production
Appl. Biochem. Biotechnol.
162
399-407
2010
Klebsiella pneumoniae
Manually annotated by BRENDA team
Tang, X.; Tan, Y.; Zhu, H.; Zhao, K.; Shen, W.
Microbial conversion of glycerol to 1,3-propanediol by an engineered strain of Escherichia coli
Appl. Environ. Microbiol.
75
1628-1634
2009
Escherichia coli, Escherichia coli SYU
Manually annotated by BRENDA team
Seo, M.Y.; Seo, J.W.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Oh, B.R.; Seo, P.S.; Choi, M.H.; Kim, C.H.
Elimination of by-product formation during production of propane-1,3-diol in Klebsiella pneumoniae by inactivation of glycerol oxidative pathway
Appl. Microbiol. Biotechnol.
84
527-534
2009
Klebsiella pneumoniae, Klebsiella pneumoniae Cu
Manually annotated by BRENDA team
Seo, J.W.; Seo, M.Y.; Oh, B.R.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Luo, L.H.; Hong, W.K.; Kim, C.H.
Identification and utilization of a 1,3-propanediol oxidoreductase isoenzyme for production of 1,3-propanediol from glycerol in Klebsiella pneumoniae
Appl. Microbiol. Biotechnol.
85
659-666
2009
Escherichia coli, Klebsiella pneumoniae
Manually annotated by BRENDA team
Zhao, L.; Zheng, Y.; Ma, X.; Wei, D.
Effects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by Klebsiella pneumoniae under micro-aerobic conditions
Bioprocess Biosyst. Eng.
32
313-320
2009
Klebsiella pneumoniae
Manually annotated by BRENDA team
Chen, Z.; Liu, H.; Liu, D.
Regulation of 3-hydroxypropionaldehyde accumulation in Klebsiella pneumoniae by overexpression of dhaT and dhaD genes
Enzyme Microb. Technol.
45
305-309
2009
Klebsiella pneumoniae
-
Manually annotated by BRENDA team
Marcal, D.; Rego, A.T.; Carrondo, M.A.; Enguita, F.J.
1,3-Propanediol dehydrogenase from Klebsiella pneumoniae: decameric quaternary structure and possible subunit cooperativity
J. Bacteriol.
191
1143-1151
2009
Klebsiella pneumoniae, Klebsiella pneumoniae (Q7WRJ3)
Manually annotated by BRENDA team
Zhao, L.; Ma, X.; Zheng, Y.; Zhang, J.; Wei, G.; Wei, D.
Over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase in Klebsiella pneumoniae and their effects on conversion of glycerol into 1,3-propanediol in resting cell system
J. Chem. Technol. Biotechnol.
84
626-632
2009
Klebsiella pneumoniae
-
Manually annotated by BRENDA team
Hao, J.; Lin, R.; Zheng, Z.; Sun, Y.; Liu, D.
3-Hydroxypropionaldehyde guided glycerol feeding strategy in aerobic 1,3-propanediol production by Klebsiella pneumoniae
J. Ind. Microbiol. Biotechnol.
35
1615-1624
2008
Klebsiella pneumoniae
Manually annotated by BRENDA team
Jeyakanthan, J.; Thamotharan, S.; Panjikar, S.; Kitamura, Y.; Nakagawa, N.; Shinkai, A.; Kuramitsu, S.; Yokoyama, S.
Expression, purification and X-ray analysis of 1,3-propanediol dehydrogenase (Aq_1145) from Aquifex aeolicus VF5
Acta Crystallogr. Sect. F
66
184-186
2010
Aquifex aeolicus
Manually annotated by BRENDA team
Zhuge, B.; Zhang, C.; Fang, H.; Zhuge, J.; Permaul, K.
Expression of 1,3-propanediol oxidoreductase and its isoenzyme in Klebsiella pneumoniae for bioconversion of glycerol into 1,3-propanediol
Appl. Microbiol. Biotechnol.
87
2177-2184
2010
Escherichia coli, Klebsiella pneumoniae, Klebsiella pneumoniae (Q59477)
Manually annotated by BRENDA team
Ma, C.; Zhang, L.; Dai, J.; Xiu, Z.
Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design
J. Biotechnol.
146
173-178
2010
Klebsiella pneumoniae, Klebsiella pneumoniae (Q7WRJ3)
Manually annotated by BRENDA team
Elleuche, S.; Fodor, K.; Klippel, B.; von der Heyde, A.; Wilmanns, M.; Antranikian, G.
Structural and biochemical characterisation of a NAD+-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications
Appl. Microbiol. Biotechnol.
97
8963-8975
2013
Oenococcus oeni (A0NIJ1), Oenococcus oeni, Oenococcus oeni ATCC BAA-1163 (A0NIJ1)
Manually annotated by BRENDA team
Oh, B.R.; Seo, J.W.; Heo, S.Y.; Luo, L.H.; Hong, W.K.; Park, D.H.; Kim, C.H.
Efficient production of 1,3-propanediol from glycerol upon constitutive expression of the 1,3-propanediol oxidoreductase gene in engineered Klebsiella pneumoniae with elimination of by-product formation
Bioprocess Biosyst. Eng.
36
757-763
2013
Klebsiella pneumoniae, Klebsiella pneumoniae (Q59477)
Manually annotated by BRENDA team
Stevens, M.J.; Vollenweider, S.; Meile, L.; Lacroix, C.
1,3-Propanediol dehydrogenases in Lactobacillus reuteri: impact on central metabolism and 3-hydroxypropionaldehyde production
Microb. Cell Fact.
10
61
2011
Lactobacillus reuteri
Manually annotated by BRENDA team
Qi, X.; Deng, W.; Wang, F.; Guo, Q.; Chen, H.; Wang, L.; He, X.; Huang, R.
Molecular cloning, co-expression, and characterization of glycerol dehydratase and 1,3-propanediol dehydrogenase from Citrobacter freundii
Mol. Biotechnol.
54
469-474
2013
Citrobacter freundii, Citrobacter freundii (P45513)
Manually annotated by BRENDA team