1.1.1.202: 1,3-propanediol dehydrogenase

This is an abbreviated version, for detailed information about 1,3-propanediol dehydrogenase, go to the full flat file.

Reaction

Propane-1,3-diol
+
NAD+
=
3-hydroxypropanal
+
NADH
+
H+

Synonyms

(NADH)-linked 1,3-PD oxidoreductase, 1,3-PD dehydrogenase, 1,3-PD oxidoreductase, 1,3-PD-DH, 1,3-PD:NAD+ oxidoreductase, 1,3-Pdiol dehydrogenase, 1,3-propanediol dehydrogenase, 1,3-propanediol oxidoreductase, 1,3-propanediol-oxidoreductase, 1,3-propanediol-oxydoreductase, 1,3-propanediol:NAD oxidoreductase, 3-hydroxypropionaldehyde reductase, ADH3, dehydrogenase, 1,3-propanediol, DhaT, lr_0030, lr_1734, NADH-linked 1,3-propanediol oxidoreductase, PDOR, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.202 1,3-propanediol dehydrogenase

Reference

Reference on EC 1.1.1.202 - 1,3-propanediol dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Johnson, E.A.; Lin, E.C.C.
Klebsiella pneumoniae 1,3-propanediol:NAD+ oxidoreductase
J. Bacteriol.
169
2050-2054
1987
Klebsiella pneumoniae
Manually annotated by BRENDA team
Heyndrickx, M.; De Vos, P.; Vancanneyt, M.; De Ley, J.
The fermentation of glycerol by Clostridium butyricum LMG 1212t2 and 1213t1 and C. pasteurianum LMG 3285
Appl. Microbiol. Biotechnol.
34
637-642
1991
Clostridium butyricum, Clostridium butyricum LMG 1212t2, Clostridium pasteurianum, Clostridium pasteurianum LMG 3285
-
Manually annotated by BRENDA team
Talarico, T.L.; Axelsson, L.T.; Novotny, J.; Fiuzat, M.; Dobrogosz, W.J.
Utilization of glycerol as a hydrogen acceptor by Lactobacillus reuteri: purification of 1,3-propanediol:NAD+ oxidoreductase
Appl. Environ. Microbiol.
56
943-948
1990
Lactobacillus reuteri
Manually annotated by BRENDA team
Abeles, R.H.; Brownstein, A.M.; Randles, C.H.
beta-Hydroxypropionaldehyde, an intermediate in the formation of 1,3-propanediol by Aerobacter aerogenes
Biochim. Biophys. Acta
41
530-531
1960
Klebsiella pneumoniae
Manually annotated by BRENDA team
Schutz, H.; Radler, F.
Anaerobic reduction of glycerol to propanediol-1,3 by Lactobacillus brevis and Lactobacillus buchneri
Syst. Appl. Microbiol.
5
169-178
1984
Lactobacillus brevis, Lactobacillus buchneri
-
Manually annotated by BRENDA team
Sprenger, G.A.; Hammer, B.A.; Johnson, E.A.; Lin, E.C.C.
Anaerobic growth of Escherichia coli on glycerol by importing genes of the dha regulon from Klebsiella pneumoniae
J. Gen. Microbiol.
135
1255-1262
1989
Klebsiella pneumoniae
Manually annotated by BRENDA team
Daniel, R.; Boenigk, R.; Gottschalk, G.
Purification of 1,3-propanediol dehydrogenase from Citrobacter freundii and cloning, sequencing, and overexpression of the corresponding gene in Escherichia coli
J. Bacteriol.
177
2151-2156
1995
Citrobacter freundii
Manually annotated by BRENDA team
Luers, F.; Seyfried, M.; Daniel, R.; Gottschalk, G.
Glycerol conversion to 1,3-propanediol by Clostridium pasteurianum: cloning and expression of the gene encoding 1,3-propanediol dehydrogenase
FEMS Microbiol. Lett.
154
337-345
1997
Clostridium pasteurianum
Manually annotated by BRENDA team
Malaoui, H.; Marczak, R.
Purification and characterization of the 1,3-propanediol dehydrogenase of Clostridium butyricum E5
Enzyme Microb. Technol.
27
399-405
2000
Clostridium butyricum, Clostridium butyricum E5
Manually annotated by BRENDA team
Abbad-Andaloussi, S.; Amine, J.; Gerard, P.; Petitdemange, H.
Effect of glucose on glycerol metabolism by Clostridium butyricum DSM 5431
J. Appl. Microbiol.
84
515-522
1998
Clostridium butyricum
Manually annotated by BRENDA team
Veiga-da-Cunha, M.; Foster, M.A.
1,3-Propanediol:NAD+ oxidoreductases of Lactobacillus brevis and Lactobacillus buchneri
Appl. Environ. Microbiol.
58
2005-2010
1992
Lactobacillus brevis, Lactobacillus buchneri
Manually annotated by BRENDA team
Zheng, Y.; Yang, C.; Baishan, F.
Cloning and sequence analysis of the dhaT gene of the 1,3-propanediol regulon from Klebsiella pneumoniae
Biotechnol. Lett.
26
251-255
2004
Klebsiella pneumoniae, Klebsiella pneumoniae (Q7WRJ3)
Manually annotated by BRENDA team
Schwarzenbacher, R.; von Delft, F.; Canaves, J.M.; Brinen, L.S.; Dai, X.; Deacon, A.M.; Elsliger, M.A.; Eshaghi, S.; Floyd, R.; Godzik, A.; Grittini, C.; Grzechnik, S.K.; Guda, C.; Jaroszewski, L.; Karlak, C.; Klock, H.E.; Koesema, E.; Kovarik, J.S.; Kreusch, A.; Kuhn, P.; Lesley, S.A.; McMullan, D.; McPhillips, T.M.; Miller, M.A.; Miller, M.D.; Morse, A.; Moy, K.; Ouyang, J.; Page, R.; Robb, A.; Rodrigues, K.; Selby, T.L.; Spraggon, G.; Stevens, R.C.; van den Bedem, H.; Velasquez, J.; Vincent, J.; Wang, X.; West, B.; Wolf, G.; Hodgson, K.O.; Wooley, J.; Wilson, I.A.
Crystal structure of an iron-containing 1,3-propanediol dehydrogenase (TM0920) from Thermotoga maritima at 1.3 A resolution
Proteins
54
174-177
2003
Thermotoga maritima (Q9X022), Thermotoga maritima
Manually annotated by BRENDA team
Nemeth, A.; Kupcsulik, B.; Sevella, B.
1,3-Propanediol oxidoreductase production with Klebsiella pneumoniae DSM2026
World J. Microbiol. Biotechnol.
19
659-663
2003
Klebsiella pneumoniae, Klebsiella pneumoniae DSM 2026
-
Manually annotated by BRENDA team
Lin, R.; Liu, H.; Hao, J.; Cheng, K.; Liu, D.
Enhancement of 1,3-propanediol production by Klebsiella pneumoniae with fumarate addition
Biotechnol. Lett.
27
1755-1759
2005
Klebsiella pneumoniae, Klebsiella pneumoniae M5a1
Manually annotated by BRENDA team
Gonzalez-Pajuelo, M.; Meynial-Salles, I.; Mendes, F.; Soucaille, P.; Vasconcelos, I.
Microbial conversion of glycerol to 1,3-propanediol: physiological comparison of a natural producer, Clostridium butyricum VPI 3266, and an engineered strain, Clostridium acetobutylicum DG1(pSPD5)
Appl. Environ. Microbiol.
72
96-101
2006
Clostridium butyricum, Clostridium butyricum VPI 3266
Manually annotated by BRENDA team
Fenghuan, W.; Huijin, Q.; He, H.; Tan, T.
High-level expression of the 1,3-propanediol oxidoreductase from Klebsiella pneumoniae in Escherichia coli
Mol. Biotechnol.
31
211-219
2005
Klebsiella pneumoniae
Manually annotated by BRENDA team
Wang, F.; Qu, H.; Zhang, D.; Tian, P.; Tan, T.
Production of 1,3-propanediol from glycerol by recombinant E. coli using incompatible plasmids system
Mol. Biotechnol.
37
112-119
2007
Klebsiella pneumoniae
Manually annotated by BRENDA team
Marcal, D.; Rego, A.T.; Fogg, M.J.; Wilson, K.S.; Carrondo, M.A.; Enguita, F.J.
Crystallization and preliminary X-ray characterization of 1,3-propanediol dehydrogenase from the human pathogen Klebsiella pneumoniae
Acta Crystallogr. Sect. F
63
249-251
2007
Klebsiella pneumoniae
Manually annotated by BRENDA team
Nemeth, A.; Sevella, B.
Development of a new bioprocess for production of 1,3-propanediol I.: modeling of glycerol bioconversion to 1,3-propanediol with Klebsiella pneumoniae enzymes
Appl. Biochem. Biotechnol.
144
47-58
2008
Klebsiella pneumoniae
Manually annotated by BRENDA team
Hao, J.; Wang, W.; Tian, J.; Li, J.; Liu, D.
Decrease of 3-hydroxypropionaldehyde accumulation in 1,3-propanediol production by over-expressing dhaT gene in Klebsiella pneumoniae TUAC01
J. Ind. Microbiol. Biotechnol.
35
735-741
2008
Klebsiella pneumoniae (A3RL85), Klebsiella pneumoniae, Klebsiella pneumoniae TUAC01 (A3RL85), Klebsiella pneumoniae TUAC01
Manually annotated by BRENDA team
Ma, Z.; Rao, Z.; Zhuge, B.; Fang, H.; Liao, X.; Zhuge, J.
Construction of a Novel Expression System in Klebsiella pneumoniae and its Application for 1,3-Propanediol Production
Appl. Biochem. Biotechnol.
162
399-407
2010
Klebsiella pneumoniae
Manually annotated by BRENDA team
Tang, X.; Tan, Y.; Zhu, H.; Zhao, K.; Shen, W.
Microbial conversion of glycerol to 1,3-propanediol by an engineered strain of Escherichia coli
Appl. Environ. Microbiol.
75
1628-1634
2009
Escherichia coli, Escherichia coli SYU
Manually annotated by BRENDA team
Seo, M.Y.; Seo, J.W.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Oh, B.R.; Seo, P.S.; Choi, M.H.; Kim, C.H.
Elimination of by-product formation during production of propane-1,3-diol in Klebsiella pneumoniae by inactivation of glycerol oxidative pathway
Appl. Microbiol. Biotechnol.
84
527-534
2009
Klebsiella pneumoniae, Klebsiella pneumoniae Cu
Manually annotated by BRENDA team
Seo, J.W.; Seo, M.Y.; Oh, B.R.; Heo, S.Y.; Baek, J.O.; Rairakhwada, D.; Luo, L.H.; Hong, W.K.; Kim, C.H.
Identification and utilization of a 1,3-propanediol oxidoreductase isoenzyme for production of 1,3-propanediol from glycerol in Klebsiella pneumoniae
Appl. Microbiol. Biotechnol.
85
659-666
2009
Escherichia coli, Klebsiella pneumoniae
Manually annotated by BRENDA team
Zhao, L.; Zheng, Y.; Ma, X.; Wei, D.
Effects of over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase on bioconversion of glycerol into 1,3-propandediol by Klebsiella pneumoniae under micro-aerobic conditions
Bioprocess Biosyst. Eng.
32
313-320
2009
Klebsiella pneumoniae
Manually annotated by BRENDA team
Chen, Z.; Liu, H.; Liu, D.
Regulation of 3-hydroxypropionaldehyde accumulation in Klebsiella pneumoniae by overexpression of dhaT and dhaD genes
Enzyme Microb. Technol.
45
305-309
2009
Klebsiella pneumoniae
-
Manually annotated by BRENDA team
Marcal, D.; Rego, A.T.; Carrondo, M.A.; Enguita, F.J.
1,3-Propanediol dehydrogenase from Klebsiella pneumoniae: decameric quaternary structure and possible subunit cooperativity
J. Bacteriol.
191
1143-1151
2009
Klebsiella pneumoniae, Klebsiella pneumoniae (Q7WRJ3)
Manually annotated by BRENDA team
Zhao, L.; Ma, X.; Zheng, Y.; Zhang, J.; Wei, G.; Wei, D.
Over-expression of glycerol dehydrogenase and 1,3-propanediol oxidoreductase in Klebsiella pneumoniae and their effects on conversion of glycerol into 1,3-propanediol in resting cell system
J. Chem. Technol. Biotechnol.
84
626-632
2009
Klebsiella pneumoniae
-
Manually annotated by BRENDA team
Hao, J.; Lin, R.; Zheng, Z.; Sun, Y.; Liu, D.
3-Hydroxypropionaldehyde guided glycerol feeding strategy in aerobic 1,3-propanediol production by Klebsiella pneumoniae
J. Ind. Microbiol. Biotechnol.
35
1615-1624
2008
Klebsiella pneumoniae
Manually annotated by BRENDA team
Jeyakanthan, J.; Thamotharan, S.; Panjikar, S.; Kitamura, Y.; Nakagawa, N.; Shinkai, A.; Kuramitsu, S.; Yokoyama, S.
Expression, purification and X-ray analysis of 1,3-propanediol dehydrogenase (Aq_1145) from Aquifex aeolicus VF5
Acta Crystallogr. Sect. F
66
184-186
2010
Aquifex aeolicus
Manually annotated by BRENDA team
Zhuge, B.; Zhang, C.; Fang, H.; Zhuge, J.; Permaul, K.
Expression of 1,3-propanediol oxidoreductase and its isoenzyme in Klebsiella pneumoniae for bioconversion of glycerol into 1,3-propanediol
Appl. Microbiol. Biotechnol.
87
2177-2184
2010
Escherichia coli, Klebsiella pneumoniae, Klebsiella pneumoniae (Q59477)
Manually annotated by BRENDA team
Ma, C.; Zhang, L.; Dai, J.; Xiu, Z.
Relaxing the coenzyme specificity of 1,3-propanediol oxidoreductase from Klebsiella pneumoniae by rational design
J. Biotechnol.
146
173-178
2010
Klebsiella pneumoniae, Klebsiella pneumoniae (Q7WRJ3)
Manually annotated by BRENDA team
Elleuche, S.; Fodor, K.; Klippel, B.; von der Heyde, A.; Wilmanns, M.; Antranikian, G.
Structural and biochemical characterisation of a NAD+-dependent alcohol dehydrogenase from Oenococcus oeni as a new model molecule for industrial biotechnology applications
Appl. Microbiol. Biotechnol.
97
8963-8975
2013
Oenococcus oeni (A0NIJ1), Oenococcus oeni, Oenococcus oeni ATCC BAA-1163 (A0NIJ1)
Manually annotated by BRENDA team
Oh, B.R.; Seo, J.W.; Heo, S.Y.; Luo, L.H.; Hong, W.K.; Park, D.H.; Kim, C.H.
Efficient production of 1,3-propanediol from glycerol upon constitutive expression of the 1,3-propanediol oxidoreductase gene in engineered Klebsiella pneumoniae with elimination of by-product formation
Bioprocess Biosyst. Eng.
36
757-763
2013
Klebsiella pneumoniae, Klebsiella pneumoniae (Q59477)
Manually annotated by BRENDA team
Stevens, M.J.; Vollenweider, S.; Meile, L.; Lacroix, C.
1,3-Propanediol dehydrogenases in Lactobacillus reuteri: impact on central metabolism and 3-hydroxypropionaldehyde production
Microb. Cell Fact.
10
61
2011
Lactobacillus reuteri
Manually annotated by BRENDA team
Qi, X.; Deng, W.; Wang, F.; Guo, Q.; Chen, H.; Wang, L.; He, X.; Huang, R.
Molecular cloning, co-expression, and characterization of glycerol dehydratase and 1,3-propanediol dehydrogenase from Citrobacter freundii
Mol. Biotechnol.
54
469-474
2013
Citrobacter freundii, Citrobacter freundii (P45513)
Manually annotated by BRENDA team
Qi, X.; Yun, J.; Qi, Y.; Zhang, H.; Wang, F.; Guo, Q.; Cao, Z.
Expression and characterization of a novel 1,3-propanediol dehydrogenase from Lactobacillus brevis
Appl. Biochem. Biotechnol.
179
959-972
2016
Lactobacillus brevis (A0A0C1Q6R1), Lactobacillus brevis, Lactobacillus brevis 6239 (A0A0C1Q6R1), Lactobacillus brevis 6239
Manually annotated by BRENDA team
Jiang, W.; Wang, S.; Wang, Y.; Fang, B.
Key enzymes catalyzing glycerol to 1,3-propanediol
Biotechnol. Biofuels
9
57
2016
Citrobacter freundii, Citrobacter freundii DSM 30040, Clostridium butyricum, Clostridium butyricum E5, Clostridium pasteurianum, Clostridium perfringens, Klebsiella pneumoniae, Klebsiella pneumoniae DSM2026, Lactobacillus brevis, Lactobacillus buchneri, Lactobacillus reuteri, Pantoea agglomerans, Thermotoga maritima
Manually annotated by BRENDA team
Lama, S.; Ro, S.; Seol, E.; Sekar, B.; Ainala, S.; Thangappan, J.; Song, H.; Seung, D.; Park, S.
Characterization of 1,3-propanediol oxidoreductase (DhaT) from Klebsiella pneumoniae J2B
Biotechnol. Bioprocess Eng.
20
971-979
2015
Klebsiella pneumoniae (Q59477), Klebsiella pneumoniae J2B (Q59477)
-
Manually annotated by BRENDA team
Qi, X.; Zhu, J.; Luo, Y.; Lin, J.; Wang, X.; Ju, Z.; Chen, F.; Zhu, X.; Chen, H.; Sun, W.; Wang, L.
Overexpression and characterization of the gene encoding 1,3-propanediol oxidoreductase of Citrobacter freundii
Key Eng. Mater.
636
121-124
2014
Citrobacter freundii (P45513)
-
Manually annotated by BRENDA team