1.1.1.202: 1,3-propanediol dehydrogenase
This is an abbreviated version!
For detailed information about 1,3-propanediol dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.202
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1.1.1.202
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pneumoniae
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klebsiella
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dehydratase
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synthesis
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fed-batch
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butyricum
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freundii
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citrobacter
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3-hydroxypropionic
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dissimilation
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1,2-propanediol
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pasteurianum
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eutropha
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biodiesel
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reuteri
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industry
- 1.1.1.202
- pneumoniae
- klebsiella
- dehydratase
- synthesis
-
fed-batch
- butyricum
- freundii
- citrobacter
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3-hydroxypropionic
-
dissimilation
- 1,2-propanediol
- pasteurianum
-
eutropha
-
biodiesel
- reuteri
- industry
Reaction
Synonyms
(NADH)-linked 1,3-PD oxidoreductase, 1,3-PD dehydrogenase, 1,3-PD oxidoreductase, 1,3-PD-DH, 1,3-PD:NAD+ oxidoreductase, 1,3-PDDH, 1,3-Pdiol dehydrogenase, 1,3-propanediol dehydrogenase, 1,3-propanediol oxidoreductase, 1,3-propanediol-oxidoreductase, 1,3-propanediol-oxydoreductase, 1,3-propanediol:NAD oxidoreductase, 3-hydroxypropionaldehyde reductase, ADH3, dehydrogenase, 1,3-propanediol, DhaT, lr_0030, lr_1734, NADH-dependent 1,3-PD dehydrogenase, NADH-dependent 1,3-propanediol oxidoreductase, NADH-linked 1,3-propanediol oxidoreductase, PDOR, YqhD
ECTree
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Inhibitors
Inhibitors on EC 1.1.1.202 - 1,3-propanediol dehydrogenase
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imidazole
activity is reduced down to 32% in the presence of 1 mM imidazole and addition of 250 mM results in complete inactivity
50 mM is necessary to obtain a 50% inhibition of enzymatic activity
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in LB media, almost no activity of PDOR in Klebsiella pneumoniae ACCC10082, while it is higher in fermentation medium
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additional information
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when the concentration of 3-hydroxypropanal increases to a higher level in medium (ac 10 mmol/L), the activity of 1,3-propanediol oxidoreductase in cell decreases correspondingly, which leads to decrease of the 3-hydroxypropanal conversion rate, then the 3-hydroxypropanal concentration increasing is accelerated furthermore
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additional information
poor effects by LiCl, DTT and sodium bisulfite at 1 mM
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additional information
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with 100 mM Na+, Li+, Mg2+ or NH4+ in addition to K+: 13-23% decrease in activity
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