1.1.1.201: 7beta-hydroxysteroid dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about 7beta-hydroxysteroid dehydrogenase (NADP+), go to the full flat file.

Reaction

a 7beta-hydroxysteroid
+
NADP+
=
a 7-oxosteroid
+
NADPH
+
H+

Synonyms

7beta-HSD, 7beta-HSDH, 7beta-hydroxysteroid dehydrogenase, More, NADP-dependent 7beta-hydroxysteroid dehydrogenase, RUMGNA_02585

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)

Temperature Stability

Temperature Stability on EC 1.1.1.201 - 7beta-hydroxysteroid dehydrogenase (NADP+)

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TEMPERATURE STABILITY
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
20
-
50% loss of activity within 60 min
20 - 60
purified recombinant His-tagged enzyme, in 100 mM MES, pH 6.0, 30 min, reductive reaction, loss of 50% activity at 50C, and inactivation at 60C