1.1.1.201: 7beta-hydroxysteroid dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about 7beta-hydroxysteroid dehydrogenase (NADP+), go to the full flat file.

Reaction

a 7beta-hydroxysteroid
+
NADP+
=
a 7-oxosteroid
+
NADPH
+
H+

Synonyms

7beta-HSD, 7beta-HSDH, 7beta-hydroxysteroid dehydrogenase, More, NADP-dependent 7beta-hydroxysteroid dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.201 7beta-hydroxysteroid dehydrogenase (NADP+)

KM Value

KM Value on EC 1.1.1.201 - 7beta-hydroxysteroid dehydrogenase (NADP+)

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
0.07
3,12-diketocholanoic acid
-
-
0.123
3,7,12-Triketo-5beta-cholanoic acid
-
-
0.145
3,7,12-triketo-5beta-cholanoyl taurine
-
-
0.087
3,7-Diketo-5beta-cholanoic acid
-
-
0.142
3alpha,12alpha-dihydroxy-7-keto-5beta-cholanoic acid
-
-
0.076
3alpha,7beta,12alpha-trihydroxy-5beta-cholanoic acid
-
-
0.009 - 0.108
3alpha,7beta-dihydroxy-5beta-cholanoic acid
0.238 - 0.909
3alpha,7beta-dihydroxy-5beta-cholanoyl glycine
0.286 - 1.639
3alpha,7beta-dihydroxy-5beta-cholanoyl taurine
0.124
3alpha-Hydroxy-7,12-diketo-5beta-cholanoic acid
-
-
0.055
3alpha-hydroxy-7-keto-5beta-cholanoic acid
-
-
0.0052
7-ketolithocholic acid
-
pH 8.0, 25°C
0.0092
Dehydrocholic acid
-
pH 8.0, 25°C
0.0053 - 0.4
NADP+
0.0045
NADPH
-
pH 8.0, 25°C
0.0062
Ursodeoxycholic acid
-
pH 8.0, 25°C