1.1.1.200: aldose-6-phosphate reductase (NADPH)

This is an abbreviated version, for detailed information about aldose-6-phosphate reductase (NADPH), go to the full flat file.

Reaction

D-sorbitol 6-phosphate
+
NADP+
=
D-glucose 6-phosphate
+
NADPH
+
H+

Synonyms

A6PR, A6PRase, alditol 6-phosphate:NADP 1-oxidoreductase, aldose-6-P reductase, aldose-6-phosphate reductase, aldose-6-phosphate reductase [NADPH], NADP-S6PDH, NADPH-dependent aldose 6-phosphate reductase, reductase, aldose 6-phosphate, S6PDH, sorbitol-6-phosphate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.200 aldose-6-phosphate reductase (NADPH)

Substrates Products

Substrates Products on EC 1.1.1.200 - aldose-6-phosphate reductase (NADPH)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-deoxy-D-glucose 6-phosphate + NADPH
?
show the reaction diagram
-
reduced at low rate
-
-
?
D-galactose 6-phosphate + NADPH
?
show the reaction diagram
-
reduced at a higher rate than D-glucose 6-phosphate
-
-
r
D-glucitol-6-phosphate
D-glucose 6-phosphate + NADPH + H+
show the reaction diagram
-
-
-
r
D-glucose 6-phosphate + NADPH
D-sorbitol 6-phosphate + NADP+
show the reaction diagram
-
-
-
-
r
D-glucose 6-phosphate + NADPH + H+
D-glucitol-6-phosphate + NADP+
show the reaction diagram
-
-
-
r
D-mannose 6-phosphate + NADPH
?
show the reaction diagram
-
reduced at low rate
-
-
?
D-sorbitol 6-phosphate + NADP+
D-glucose 6-phosphate + NADPH + H+
show the reaction diagram
additional information
?
-