1.1.1.2: alcohol dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

a primary alcohol
+
NADP+
=
an aldehyde
+
NADPH
+
H+

Synonyms

2° Adh, 3-DG-reducing enzyme, AAur_2040, ADH, ADH-1, ADH-2, ADH-I, ADH-II, ADH2, Adh319, ADH4, Adh6, AdhA, AdhB, AKR1A1, AKR1A4, alcohol dehydrogenase C, alcohol dehydrogenase [NADP(+)], Alcohol dehydrogenase [NADP+], aldehyde reductase, aldehyde reductase (NADPH2), aldehyde/ketone reductase, aldo-keto reductase, Aldo-keto reductase family 1 member A1, aldose reductase, ALDR, alipathic aldehyde reductase, ALR, ALR 1, ALR1, BdhA, bovine brain aldehyde reductase, D-glucuronate reductase, daunorubicin reductase, DRD, EhADH1, Gre2p, hexogenate dehydrogenase, high-Km aldehyde reductase, HvADH2, L-hexonate dehydrogenase, LB-RADH, LBADH, liver alcohol dehydrogenase, low-Km aldehyde reductase, mevaldate reductase, Mpd1, NADP(H)-dependent alcohol dehydrogenase, NADP-alcohol dehydrogenase, NADP-aldehyde reductase, NADP-dependent aldehyde reductase, NADP-linked aryl alcohol dehydrogenase, NADPH-aldehyde reductase, NADPH-cytochrome c reductase, NADPH-dependent aldehyde reductase, NADPH-dependent FALDR, NADPH-dependent fatty aldehyde reductase, NADPH-linked aldehyde reductase, nonspecific succinic semialdehyde reductase, Octopine dehydrogenase, putative iron alcohol dehydrogenase, PyAeADHII, rabbit kidney aldehyde-ketone reductase, RADH, ScADHVI, short-chain ADH, short-chain alcohol dehydrogenase, short-chain dehydrogenase/reductase, TBADH, TbADH1, Teth39_1597, Teth514_0564, TPN-L-hexonate dehydrogenase, TPNH-linked aldehyde reductase, TPNH-specific aldehyde reductase, triphosphopyridine nucleotide-linked aldehyde reductase, TsAdh319, Y63 protein, yeast alcohol dehydrogenase, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.2 alcohol dehydrogenase (NADP+)

pH Optimum

pH Optimum on EC 1.1.1.2 - alcohol dehydrogenase (NADP+)

Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
5.9
-
aldehyde reductase I
6 - 6.5
-
AR1 and AR3
6.2
-
aldehyde reductase II
6.5
-
reduction reaction, assay at
6.5 - 9
-
NAD(P)+ reduction
6.6
-
reduction of p-nitrobenzaldehyde in presence of NADPH
6.7 - 6.8
6.8 - 7
-
ethanol as substrate
7 - 8
-
propionaldehyde as substrate
7.8 - 9.5
-
isoform ADH-2; isoform ADH-II
8 - 9
-
isoform ADH-1; isoform ADH-I
8.5 - 9
-
in glycineNaOH buffer with heptanal as substrate
9 - 9.5
-
oxidation of benzyl alcohol in presence of NADP+
9
-
alcohol-oxidation
9 - 9.5
-
n-propanol as substrate
9.4 - 10.2
-
80°C, optimal pH for ethanol oxidation
9.5
-
n-heptanol oxidation
10 - 11
alcohol oxidation
10
-
oxidation of 3-pyridinemethanol
10.3 - 10.5
for ethanol oxidation
11
-
oxidation of alcohol