1.1.1.2: alcohol dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

a primary alcohol
+
NADP+
=
an aldehyde
+
NADPH
+
H+

Synonyms

2 Adh, 3-DG-reducing enzyme, AAur_2040, ADH, ADH-1, ADH-2, ADH-I, ADH-II, ADH2, Adh319, ADH4, Adh6, AdhA, AdhB, AKR1A1, AKR1A4, alcohol dehydrogenase C, alcohol dehydrogenase [NADP(+)], Alcohol dehydrogenase [NADP+], aldehyde reductase, aldehyde reductase (NADPH2), aldehyde/ketone reductase, aldo-keto reductase, Aldo-keto reductase family 1 member A1, aldose reductase, ALDR, alipathic aldehyde reductase, ALR, ALR 1, ALR1, BdhA, bovine brain aldehyde reductase, D-glucuronate reductase, daunorubicin reductase, DRD, EhADH1, Gre2p, hexogenate dehydrogenase, high-Km aldehyde reductase, HvADH2, L-hexonate dehydrogenase, LB-RADH, LBADH, liver alcohol dehydrogenase, low-Km aldehyde reductase, mevaldate reductase, Mpd1, NADP(H)-dependent alcohol dehydrogenase, NADP-alcohol dehydrogenase, NADP-aldehyde reductase, NADP-dependent aldehyde reductase, NADP-linked aryl alcohol dehydrogenase, NADPH-aldehyde reductase, NADPH-cytochrome c reductase, NADPH-dependent aldehyde reductase, NADPH-dependent FALDR, NADPH-dependent fatty aldehyde reductase, NADPH-linked aldehyde reductase, nonspecific succinic semialdehyde reductase, Octopine dehydrogenase, putative iron alcohol dehydrogenase, PyAeADHII, rabbit kidney aldehyde-ketone reductase, RADH, ScADHVI, short-chain ADH, short-chain alcohol dehydrogenase, short-chain dehydrogenase/reductase, TBADH, TbADH1, Teth39_1597, Teth514_0564, TPN-L-hexonate dehydrogenase, TPNH-linked aldehyde reductase, TPNH-specific aldehyde reductase, triphosphopyridine nucleotide-linked aldehyde reductase, TsAdh319, Y63 protein, yeast alcohol dehydrogenase, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.2 alcohol dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.2 - alcohol dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(+)-camphorquinoneone + NADPH
? + NADP+
show the reaction diagram
(-)-camphorquinoneone + NADPH
? + NADP+
show the reaction diagram
-
relative activity 2%
-
-
?
(2E)-hex-2-enal + NADPH + H+
(2E)-2-hexen-1-ol + NADP+
show the reaction diagram
-
-
-
-
r
(2E,4E)-hexa-2,4-dienal + NAD(P)H + H+
(2E,4E)-6-hydroxyhexa-2,4-dienal + NAD(P)+
show the reaction diagram
-
-
-
-
-
(2R,3R)-2,3-butanediol + NADP+
(R)-2-acetoin + NADPH + H+
show the reaction diagram
the enzyme shows higher oxidation activities on the (2R,3R)-(-)-2,3-butanediol and meso-2,3-butanediol than on the (2S,3S)-(+)-2,3-butanediol, indicating that the enzyme predominantly oxidizes the R-hydroxyl group of 2,3-butanediol and minorly functions on the S-hydroxyl group. When meso-2,3-butanediol is oxidized, (S)-2-acetoin is the predominant product, with an enantiomeric excess (ee) of 88%, while oxidation of (2R,3R)-2,3-butanediol results in the production of (R)-2-acetoin with higher stereoselectivity (94% ee)
-
-
r
(2S)-methyl-1-butanol + NADP+
(2S)-methylbutanal + NADPH
show the reaction diagram
-
39% activity compared to cinnamyl alcohol
-
-
r
(2S,3S)-2,3-butanediol + NADP+
(S)-2-acetoin + NADPH + H+
show the reaction diagram
the enzyme shows higher oxidation activities on the (2R,3R)-(-)-2,3-butanediol and meso-2,3-butanediol than on the (2S,3S)-(+)-2,3-butanediol, indicating that the enzyme predominantly oxidizes the R-hydroxyl group of 2,3-butanediol and minorly functions on the S-hydroxyl group. When meso-2,3-butanediol is oxidized, (S)-2-acetoin is the predominant product, with an enantiomeric excess (ee) of 88%, while oxidation of meso-2,3-butanediol results in the production of (R)-2-acetoin with higher stereoselectivity (94% ee)
-
-
r
(4-hydroxy-3-[3-methyl-3-butene-1-ynyl]benzaldehyde) + NADPH + H+
(4-hydroxy-3-[3-methyl-3-butene-1-ynyl]benzyl alcohol) + NADP+
show the reaction diagram
-
eutypine, a toxin produced by Eutypa lata, the causal agent of Eutypa dieback in the grapevine Vitis vinifera
eutypinol, non-toxic metabolite
ir
(R)-1-phenyl-2-propanol + NADP+
phenylacetone + NADPH + H+
show the reaction diagram
-
-
-
-
?
(R)-2-butanol + NADP+
2-butanone + NADPH + H+
show the reaction diagram
the enzyme shows a slight preference for the (S)-2-butanol over (R)-2-butanol
-
-
?
(S)-1-phenyl-2-propanol + NADP+
phenylacetone + NADPH + H+
show the reaction diagram
-
-
-
-
r
(S)-2-butanol + NADP+
2-butanone + NADPH + H+
show the reaction diagram
the enzyme shows a slight preference for the (S)-2-butanol over (R)-2-butanol
-
-
?
(S)-2-butanol + NADP+
butanone + NADPH + H+
show the reaction diagram
-
196% of the activity with 2-propanol, 2fold preference for (S)-2-butanol over (RS)-2-butanol
-
-
?
1,2-butanediol + NADP+
? + NADPH + H+
show the reaction diagram
25.6% of the activity compared to the substrate 2-butanol
-
-
?
1,2-cyclohexanedione + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
1,2-propanediol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
?
1,3-butanediol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
?
1,3-butanediol + NADP+
? + NADPH + H+
show the reaction diagram
35.4% of the activity compared to the substrate 2-butanol
-
-
?
1,3-propanediol + NADP+
?
show the reaction diagram
-
-
-
-
?
1,3-propanediol + NADP+
? + NADPH
show the reaction diagram
1,4-butanediol + NADP+
?
show the reaction diagram
-
-
-
-
?
1,5-pentanediol + NADP+
?
show the reaction diagram
-
-
-
-
?
1,5-pentanediol + NADP+
? + NADPH + H+
show the reaction diagram
1-butanol + NADP+
butanal + NADPH
show the reaction diagram
1-butanol + NADP+
butanal + NADPH + H+
show the reaction diagram
1-butanol + NADP+
butyraldehyde + NADPH + H+
show the reaction diagram
1-heptanol + NADP+
heptanal + NADPH + H+
show the reaction diagram
1-hexanol + NADP+
hexanal + NADPH
show the reaction diagram
1-hexanol + NADP+
hexanal + NADPH + H+
show the reaction diagram
1-octanol + NADP+
octanal + NADPH
show the reaction diagram
1-octanol + NADP+
octanal + NADPH + H+
show the reaction diagram
1-pentanol + NADP+
n-pentanal + NADPH
show the reaction diagram
1-pentanol + NADP+
n-pentanal + NADPH + H+
show the reaction diagram
-
-
-
-
?
1-pentanol + NADP+
pentanal + NADPH
show the reaction diagram
1-pentanol + NADP+
pentanal + NADPH + H+
show the reaction diagram
1-phenyl-2-butanone + NADPH + H+
(S)-1-phenyl-2-butanol + NADP+
show the reaction diagram
-
-
-
-
?
1-propanol + NADP+
?
show the reaction diagram
-
-
-
-
?
1-propanol + NADP+
propanal + NADPH
show the reaction diagram
-
16% activity compared to cinnamyl alcohol
-
-
r
1-propanol + NADP+
propanal + NADPH + H+
show the reaction diagram
13-cis-retinal + NADPH
13-cis-retinol + NADP+
show the reaction diagram
-
-
-
-
?
2,2,2-trifluoro-1-phenylethanone + NADPH + H+
(1S)-2,2,2-trifluoro-1-phenylethanol + NADP+
show the reaction diagram
-
-
99% conversion, 99% enantiomeric excess
-
?
2,2-difluoro-1-phenylethanone + NADPH + H+
(1S)-2,2-difluoro-1-phenylethanol + NADP+
show the reaction diagram
-
-
99% conversion, 99% enantiomeric excess
-
?
2,3-pentanedione + NADPH + H+
? + NADP+
show the reaction diagram
2,4-hexadienal + NADPH
2,4-hexadien-1-ol + NADP+
show the reaction diagram
-
-
-
-
?
2,4-pentanediol + NADP+
? + NADPH + H+
show the reaction diagram
9.2% of the activity compared to the substrate 2-butanol
-
-
?
2,5-hexanedione + NADP+
(2S,5S)-hexanediol + NADPH + H+
show the reaction diagram
-
-
-
-
r
2-(S)-methylbutanol + NADP+
(2S)-2-methylbutanal + NADPH
show the reaction diagram
-
7% of activity with cinnamyl alcohol
-
-
r
2-butanol + NADP+
2-butanone + NADPH
show the reaction diagram
-
2% of activity with cinnamyl alcohol
-
-
r
2-butanol + NADP+
2-butanone + NADPH + H+
show the reaction diagram
the enzyme does not possess stereoselectivity on 2-butanol or 2-butanone as substrate
-
-
r
2-butanol + NADP+
?
show the reaction diagram
2-butanol + NADP+
butan-2-one + NADPH
show the reaction diagram
2-butanol + NADP+
butanone + NADPH
show the reaction diagram
-
1% activity compared to cinnamyl alcohol
-
-
r
2-butanone + NADP+
2-butanol + NADPH + H+
show the reaction diagram
-
-
-
-
r
2-butanone + NADPH + H+
2-butanol + NADP+
show the reaction diagram
the enzyme does not possess stereoselectivity on 2-butanol or 2-butanone as substrate
-
-
r
2-chloroheptanal + NADPH
2-chloroheptanol + NADP+
show the reaction diagram
-
-
-
-
r
2-decanone + NADPH
2-decanol + NADP+
show the reaction diagram
-
-
-
-
?
2-fluoro-1-(4-chlorophenyl)ethanone + NADPH + H+
(1S)-2-fluoro-1-(4-chlorophenyl)ethanol + NADP+
show the reaction diagram
-
-
99% conversion, 99% enantiomeric excess
-
?
2-fluoro-1-(4-fluorophenyl)ethanone + NADPH + H+
(1S)-2-fluoro-1-(4-fluorophenyl)ethanol + NADP+
show the reaction diagram
-
-
99% conversion, 99% enantiomeric excess
-
?
2-fluoro-1-(4-iodophenyl)ethanone + NADPH + H+
(1S)-2-fluoro-1-(4-iodophenyl)ethanol + NADP+
show the reaction diagram
-
-
99% conversion, 99% enantiomeric excess
-
?
2-fluoro-1-phenylethanone + NADPH + H+
(1S)-2-fluoro-1-phenylethanol + NADP+
show the reaction diagram
-
-
99% conversion, 99% enantiomeric excess
-
?
2-heptanol + NADP+
heptan-2-one + NADPH
show the reaction diagram
-
-
-
-
r
2-methoxybenzaldehyde + NADPH + H+
2-methoxybenzyl alcohol + NADP+
show the reaction diagram
2-methyl-1-propanol + NADP+
2-methylpropanal + NADPH
show the reaction diagram
2-methylbutanal + NADPH
2-methyl-1-butanol + NADP+
show the reaction diagram
2-methylbutanal + NADPH
2-methylbutanol + NADP+
show the reaction diagram
-
-
-
-
r
2-methylbutanol + NADP+
2-methylbutyraldehyde + NADPH + H+
show the reaction diagram
-
24% activity with 1 mM 2-methylbutanol, 22% activity with 10 mM 2-methylbutanol
-
-
r
2-methylbutanol + NADP+
? + NADPH + H+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.5 mM NADP+, 24% relative activity with 1 mM or 22% relative activity with 10 mM substrate
-
-
?
2-methylpropanal + NADPH
2-methyl-1-propanol + NADP+
show the reaction diagram
2-methylpropanol + NADP+
2-methylpropanal + NADPH
show the reaction diagram
-
1% of activity with cinnamyl alcohol
-
-
r
2-methylundecanal + NADPH
2-methylundecanol + NADP+
show the reaction diagram
-
-
-
-
?
2-pentanol + NADP+
2-pentanone + NADPH + H+
show the reaction diagram
2-pentanol + NADP+
pentan-2-one + NADPH
show the reaction diagram
-
-
-
-
r
2-pentanol + NADP+
pentan-2-one + NADPH + H+
show the reaction diagram
-
67% of the activity with 2-propanol
-
-
?
2-pentanone + NADP+
2-pentanol + NADPH + H+
show the reaction diagram
-
-
-
-
r
2-pentanone + NADPH + H+
2-pentanol + NADP+
show the reaction diagram
86.2% of the activity compared to the substrate 2-butanone
-
-
r
2-phenylacetaldehyde + NADPH + H+
2-phenylethanol + NADP+
show the reaction diagram
Thermococcus paravinellae
-
-
-
-
r
2-phenylethanol + NADP+
2-phenylacetaldehyde + NADPH + H+
show the reaction diagram
2-phenylethanol + NADP+
phenylacetaldehyde + NADPH
show the reaction diagram
-
23% activity compared to cinnamyl alcohol
-
-
r
2-phenylethanol + NADP+
phenylacetaldehyde + NADPH + H+
show the reaction diagram
2-propanol + NADP+
acetone + NADPH
show the reaction diagram
2-propanol + NADP+
acetone + NADPH + H+
show the reaction diagram
2-propanone + NADP+
2-propanol + NADPH + H+
show the reaction diagram
-
-
-
-
r
2-propen-1-ol + NADP+
acrylaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
3,4-dihydro-1(2H)-naphthalenone + NADPH + H+
1,2,3,4-tetrahydronaphthalen-1-ol + NADP+
show the reaction diagram
3,4-dihydroxyphenylacetaldehyde + NADPH + H+
3,4-dihydroxyphenylethanol + NADP+
show the reaction diagram
-
-
-
-
r
3,4-dihydroxyphenylglycolaldehyde + NADPH
? + NADP+
show the reaction diagram
3-cyanobenzaldehyde + NADPH
3-cyanobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
3-deoxyglucosone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
3-heptanone + NADPH
3-heptanol + NADP+
show the reaction diagram
-
-
-
-
?
3-hexanol + NADP+
hexan-3-one + NADPH
show the reaction diagram
-
-
-
-
r
3-methyl-1,5-pentanediol + NADP+
?
show the reaction diagram
3-methyl-1-butanol + NADP+
3-methylbutanal + NADPH
show the reaction diagram
-
40% activity compared to cinnamyl alcohol
-
-
r
3-methylbutanal + NADPH
3-mehtyl-1-butanol + NADP+
show the reaction diagram
-
84% of activity with cinnamaldehyde
-
-
r
3-methylbutanal + NADPH
3-methyl-1-butanol + NADP+
show the reaction diagram
-
79% activity compared to cinnamaldehyde
-
-
r
3-methylbutanal + NADPH
3-methylbutanol + NADP+
show the reaction diagram
-
-
-
-
r
3-methylbutanol + NADP+
3-methylbutanal + NADPH
show the reaction diagram
-
15% of activity with cinnamyl alcohol
-
-
r
3-octanone + NADPH
3-octanol + NADP+
show the reaction diagram
-
-
-
-
?
3-pyridinecarboxaldehyde + NADPH
3-pyridinemethanol + NADP+
show the reaction diagram
3-pyridinemethanol + NADP+
3-pyridinecarboxaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
4-benzoylpyridine + ?
?
show the reaction diagram
-
-
-
-
r
4-carboxyacetophenone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
4-carboxyphenylglyoxal + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
4-hydroxy-3-methoxybenzyl alcohol + NADP+
4-hydroxy-3-methoxybenzaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
4-hydroxy-3-methoxyphenethylene glycol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
r
4-hydroxybenzaldehyde + NADPH + H+
4-hydroxybenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
4-hydroxybutyrate + NADP+
4-ketobutyrate + NADPH
show the reaction diagram
-
-
-
-
r
4-hydroxynonenal + NADPH
4-hydroxynonenol + NADP+
show the reaction diagram
-
30% of activity with cinnamaldehyde
-
-
r
4-methoxybenzaldehyde + NADPH + H+
4-methoxybenzyl alcohol + NADP+
show the reaction diagram
4-methylbenzyl alcohol + NADP+
4-methylbenzaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
4-nitroacetophenone + NADPH
1-(4-nitrophenyl)ethanol + NADP+
show the reaction diagram
-
-
-
-
?
4-phenyl-2-butanone + NADPH + H+
(S)-4-phenyl-2-butanol + NADP+
show the reaction diagram
-
-
-
-
?
4-pyridinecarboxaldehyde + NADPH
4-pyridinemethanol + NADP+
show the reaction diagram
5-(hydroxymethyl)furan-2-carbaldehyde + NADPH + H+
(furan-2,5-diyl)dimethanol + NADP+
show the reaction diagram
5-hydroxyindoleacetaldehyde + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
5-hydroxymethylfurfural + NADPH + H+
5-hydroxymethylfurfuryl alcohol + NADP+
show the reaction diagram
5alpha-dihydrotestosterone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
9-cis-retinal + NADPH
9-cis-retinol + NADP+
show the reaction diagram
-
-
-
-
r
9-cis-retinol + NADP+
9-cis-retinal + NADPH
show the reaction diagram
-
-
-
-
r
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly + NADH + H+
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-al + NADPH + H+
Ac-D-Leu-D-Trp-D-Leu-D-Trp-Gly-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-D-Ala-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-Gly-S-CoA + NADPH + H+
?
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Ala-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Asp-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu- + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Leu-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Lys-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe + NADH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-al + NADPH + H+
Ac-D-Leu-L-Trp-D-Leu-L-Trp-L-Phe-ol + NADP+
show the reaction diagram
-
-
-
-
-
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly- + NADH + H+
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-al + NAD+ + H2O
show the reaction diagram
-
-
-
-
-
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-al + NADPH + H+
Ac-L-Leu-L-Trp-L-Leu-L-Trp-Gly-ol + NADP+
show the reaction diagram
-
-
-
-
-
acetaldehyde + NADPH + H+
ethanol + NADP+
show the reaction diagram
acetoin + NADPH + H+
2,3-butanediol + NADP+
show the reaction diagram
93% of the activity compared to the substrate 2-butanone. The racemic R/S-acetoin is used since neither R- nor S-acetoin is commercially available. Consistently, the reduction of racemic R/S-acetoin formed (2R,3R)-2,3-butanediol (presumably from R-acetoin) and meso-2,3-butanediol (presumably from S-acetoin) with extremely high stereoselectivity (99% ee over (2S,3S)-(+)-2,3-butanediol)
-
-
r
acetoin + NADPH + H+
butan-2,3-diol + NADP+
show the reaction diagram
-
isozyme AR3
-
-
?
acetone + NADPH
2-propanol + NADP+
show the reaction diagram
-
-
-
-
?
acetone + NADPH + H+
2-propanol + NADP+
show the reaction diagram
149% of the activity compared to the substrate 2-butanone
-
-
r
acetone + NADPH + H+
propan-2-ol + NADP+
show the reaction diagram
-
about 13% of the activity with butan-2-ol
-
-
?
acetophenone + NADH + H+
1-phenylethanol + NAD+
show the reaction diagram
-
recombinant mutant G37D
recombinate mutant G37D
-
r
acetophenone + NADPH
(R)-1-phenylethanol + NADP+
show the reaction diagram
-
catalysed by Escherichia coli coexpressing enzyme with NAD+-dependent formate dehydrogenase and pyridine nucleotide transhydrogenase genes pnta and pntb
-
-
?
acetophenone + NADPH
1-phenylethanol + NADP+
show the reaction diagram
-
-
-
-
?
acetophenone + NADPH + H+
(S)-1-phenylethanol + NADP+
show the reaction diagram
-
-
-
-
r
acetophenone + NADPH + H+
1-phenylethanol + NADP+
show the reaction diagram
-
recombinant wild-type
recombinant wild-type
-
r
acetyl-CoA + NADPH
acetaldehyde + CoA + NADP+
show the reaction diagram
-
-
-
-
?
acrolein + NADPH
propenol + NADP+
show the reaction diagram
-
-
-
-
r
adonitol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
r
aldehyde + NADPH + H+
alcohol + NADP+
show the reaction diagram
-
the physiological role of this enzyme is likely to catalyze the reduction of aldehydes to alcohols
-
-
?
all-trans-retinal + NADPH + H+
all-trans-retinol + NADP+
show the reaction diagram
-
-
-
-
r
all-trans-retinol + NADP+
all-trans-retinal + NADPH
show the reaction diagram
-
-
-
-
r
allactose + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
alpha-diketone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
androstane-3,17-dione + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
anisaldehyde + NADPH
4-methoxybenzyl alcohol + NADP+
show the reaction diagram
anisaldehyde + NADPH + H+
anisyl alcohol + NADP+
show the reaction diagram
anisyl alcohol + NADP+
anisaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
benzalacetone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
benzaldehyde + NADPH
benzyl alcohol + NADP+
show the reaction diagram
benzaldehyde + NADPH + H+
benzyl alcohol + NADP+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.2 mM NADPH, 30% relative activity with 0.1 mM or 14% relative activity with 1 mM substrate
-
-
r
benzoic aldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
benzyl alcohol + NADP+
benzaldehyde + NADPH
show the reaction diagram
benzyl alcohol + NADP+
benzaldehyde + NADPH + H+
show the reaction diagram
butan-1-ol + NADP+
butanal + NADPH + H+
show the reaction diagram
butan-2-ol + NADP+
butanone + NADPH + H+
show the reaction diagram
butanal + NADPH + H+
1-butanol + NADP+
show the reaction diagram
butanal + NADPH + H+
butan-1-ol + NADP+
show the reaction diagram
butanal + NADPH + H+
butanol + NADP+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.2 mM NADPH, 73% relative activity with 0.1 mM or 120% relative activity with 1 mM substrate
-
-
r
butanaldehyde + NADPH
butanol + NADP+
show the reaction diagram
-
-
-
-
r
butane 2,3-dione + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
butane-1,2-diol + NADP+
butanal-2-ol + NADPH
show the reaction diagram
-
2% activity compared to cinnamyl alcohol
-
-
r
butane-1,3-diol + NADP+
butanal-3-ol + NADPH
show the reaction diagram
-
5% activity compared to cinnamyl alcohol
-
-
r
butane-1,4-diol + NADP+
butanal-4-ol + NADPH
show the reaction diagram
-
8% activity compared to cinnamyl alcohol
-
-
r
butanol + NADP+
butanal + NADPH
show the reaction diagram
butanol + NADP+
butanal + NADPH + H+
show the reaction diagram
butanone + NADPH + H+
butan-2-ol + NADP+
show the reaction diagram
-
-
-
-
r
butyraldehyde + NADPH + H+
1-butanol + NADP+
show the reaction diagram
112.4% of the activity compared to the substrate 2-butanone
-
-
r
butyraldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
cellobiose + NADP+
? + NADPH + H+
show the reaction diagram
chloral hydrate + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
cinnamaldehyde + NADPH
cinnamic alcohol + NADP+
show the reaction diagram
5% of activity with acetaldehyde
-
-
r
cinnamaldehyde + NADPH
cinnamyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
cinnamaldehyde + NADPH + H+
cinnamyl alcohol + NADP+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.2 mM NADPH, 61% relative activity with 0.1 mM or 7% relative activity with 1 mM substrate
-
-
r
cinnamic aldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
cinnamyl alcohol + NADP+
cinnamaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
cinnamyl alcohol + NADP+
cinnamaldehyde + NADPH + H+
show the reaction diagram
cinnamyl alcohol + NADP+
cinnamylaldehyde + NADPH
show the reaction diagram
-
-
-
-
r
cis-11-hexadecenal + NADPH
cis-11-hexadecenol + NADP+
show the reaction diagram
-
87% relative activity
-
-
ir
coniferaldehyde + NADPH
coniferyl alcohol + NADP+
show the reaction diagram
coniferyl alcohol + NADP+
coniferaldehyde + NADPH + H+
show the reaction diagram
-
7% activity compared to cinnamyl alcohol
-
-
r
coniferyl alcohol + NADP+
coniferylaldehyde + NADPH + H+
show the reaction diagram
-
27% of activity with cinnamyl alcohol
-
-
r
cyclohexancarbaldehye + NADPH
cyclohexanol + NADP+
show the reaction diagram
3% of activity with acetaldehyde
-
-
r
cyclohexanol + NADP+
cyclohexanal + NADPH
show the reaction diagram
-
-
-
-
r
cyclohexanol + NADP+
cyclohexancarbaldehyde + NADPH
show the reaction diagram
14% of activity with ethanol
-
-
r
cyclohexanol + NADP+
cyclohexanone + NADPH + H+
show the reaction diagram
-
about 15% of the activity with butan-2-ol
-
-
?
cyclohexanone + NADPH
cyclohexanol + NADP+
show the reaction diagram
cyclopentanol + NADP+
cyclopentanal + NADPH
show the reaction diagram
-
-
-
-
r
D-arabinose + NADP+
D-arabitol + NADPH + H+
show the reaction diagram
-
200% of the activity with 2-propanol. D-arabinose is preferred over L-arabinose
-
-
?
D-arabinose + NADPH
? + NADP+
show the reaction diagram
D-arabitol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
r
D-erythrose + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
D-fructose + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
D-galactose + NADPH
? + NADP+
show the reaction diagram
D-galacturonate + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
D-glucose + NADP+
? + NADPH + H+
show the reaction diagram
D-glucose + NADPH
? + NADP+
show the reaction diagram
D-glucose + NADPH + H+
sorbitol + NADP+
show the reaction diagram
D-glucuronate + NADPH
?
show the reaction diagram
D-glucuronate + NADPH
L-gulonate + NADP+
show the reaction diagram
D-glucuronate + NADPH + H+
?
show the reaction diagram
D-glucuronate + NADPH + H+
? + NADP+
show the reaction diagram
D-glucuronolactone + NADPH
? + NADP+
show the reaction diagram
D-glyceraldehyde + NADPH + H+
glycerol + NADP+
show the reaction diagram
D-lactaldehyde + NADPH + H+
propane-1,2-diol + NADP+
show the reaction diagram
D-ribose + NADPH
? + NADP+
show the reaction diagram
D-sorbitol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
r
D-xylose + NADP+
? + NADPH + H+
show the reaction diagram
-
246% of the activity with 2-propanol
-
-
?
D-xylose + NADPH
? + NADP+
show the reaction diagram
daunorubicin + NADPH
? + NADP+
show the reaction diagram
decanal + NADPH
decanol + NADP+
show the reaction diagram
-
no detectable catalysis of the reverse reaction, the oxidation of decanol by NADP+. 100% relative activity
-
-
ir
decanal + NADPH + H+
decanol + NADP+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.2 mM NADPH, 21% relative activity with 0.1 mM or 22% relative activity with 1 mM substrate
-
-
r
decanol + NADP+
decanal + NADPH + H+
show the reaction diagram
dehydro-L-ascorbate + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
diacetyl + + NADPH + H+
acetoin + NADP+
show the reaction diagram
the enzyme can not oxidize acetoin to diacetyl
-
-
ir
diacetyl + NADPH
? + NADP+
show the reaction diagram
dimethylglyoxal + NADPH + H+
? + NADP+
show the reaction diagram
-
270% of the activity with pyruvaldehyde
-
-
?
DL-glyceraldehyde + NADPH + H+
? + NADP+
show the reaction diagram
DL-glyceraldehyde + NADPH + H+
DL-glycerol + NADP+
show the reaction diagram
-
-
-
-
?
DL-glyceraldehyde + NADPH + H+
glycerol + NADP+
show the reaction diagram
dodecanal + NADPH
dodecanol + NADP+
show the reaction diagram
-
55% relative activity
-
-
ir
erythritol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
r
ethanol + NAD+
acetaldehyde + NADH + H+
show the reaction diagram
ethanol + NADP+
acetaldehyde + NADPH + H+
show the reaction diagram
ethyl 4-bromo-3-oxobutanoate + NADPH
(R)-4-bromo-3-hydroxybutanoic acid ethyl ester + NADP+
show the reaction diagram
-
-
-
-
?
ethyl 4-chloro-3-oxobutanoate + NADPH + H+
(R)-4-chloro-3-hydroxybutanoic acid ethyl ester + NADP+
show the reaction diagram
-
-
-
-
?
ethyl 4-chloro-3-oxobutanoate + NADPH + H+
ethyl (S)-4-chloro-3-hydroxybutanoate + NADP+
show the reaction diagram
ethyl-4-chloro-3-oxobutanoate + NADPH + H+
ethyl-4-chloro-3-hydroxybutanoate + NADP+
show the reaction diagram
ethylacetoacetate + NADPH
ethyl L-(+)-3-hydroxybutyrate + NADP+
show the reaction diagram
ethylene glycol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
?
formaldehyde + NADPH
methanol + NADP+
show the reaction diagram
formaldehyde + NADPH + H+
methanol + NADP+
show the reaction diagram
furaldehyde + NADPH
furfuryl alcohol + NADP+
show the reaction diagram
-
-
-
-
?
furan-2-carbaldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
furfural + NADH + H+
furfuryl alcohol + NAD+
show the reaction diagram
furfural + NADPH
furfuryl alcohol + NADP+
show the reaction diagram
furfural + NADPH + H+
furfuryl alcohol + NADP+
show the reaction diagram
glucuronate + NADPH
?
show the reaction diagram
glucuronate + NADPH + H+
?
show the reaction diagram
glutaraldehyde + NADPH
? + NADP+
show the reaction diagram
5% of activity with acetaldehyde
-
-
r
glycerol + NADP+
DL-glyceraldehyde + NADPH
show the reaction diagram
glycolaldehyde + NADPH
ethane-1,2-diol + NADP+
show the reaction diagram
heptanal + NADPH
1-heptanol + NADP+
show the reaction diagram
heptanal + NADPH + H+
heptanol + NADP+
show the reaction diagram
-
-
-
-
?
heptanaldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
hexadecanol + NADP+
hexadecanal + NADPH
show the reaction diagram
-
-
-
-
r
hexan-1-ol + NADP+
hexanal + NADPH + H+
show the reaction diagram
hexanal + NADPH + H+
1-hexanol + NADP+
show the reaction diagram
hexanal + NADPH + H+
hexanol + NADP+
show the reaction diagram
hexanal + NADPH + H+
n-hexanol + NADP+
show the reaction diagram
-
-
-
-
?
hexanaldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
hexanol + NADP+
hexanal + NADPH
show the reaction diagram
hexanol + NADP+
hexanal + NADPH + H+
show the reaction diagram
hexyl alcohol + NADP+
?
show the reaction diagram
the native enzyme shows 137.8% activity with hexyl alcohol compared to ethanol
-
-
?
hexyl alcohol + NADP+
hexanal + NADPH + H+
show the reaction diagram
-
-
-
-
?
hydroxyindol-3-ylacetaldehyde + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
hydroxypyruvate + ?
?
show the reaction diagram
-
-
-
-
r
indol-3-ylacetaldehyde + NADPH
indol-3-ethanol + NADP+
show the reaction diagram
indolacetaldehyde sodium bisulfate complex + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
iodoacetaldehyde + NADPH
iodoethan-2-ol + NADP+
show the reaction diagram
-
-
-
-
r
iodohexadecanal + NADPH
iodohexadecanol + NADP+
show the reaction diagram
-
-
-
-
r
isoamyl alcohol + NADP+
3-methylbutanol + NADPH
show the reaction diagram
18% of activity with ethanol
-
-
r
isobutanol + NADP+
isobutanal + NADPH + H+
show the reaction diagram
isobutanol + NADP+
isobutanol + NADPH + H+
show the reaction diagram
Thermococcus paravinellae
-
93% of the activity with ethanol
-
-
r
isobutanol + NADP+
isobutyl aldehyde + NADPH + H+
show the reaction diagram
Moorella sp.
-
isoform AdhA, 221% of the activity with acetaldehyde
-
-
r
isobutyl aldehyde + NADPH + H+
isobutanol + NADP+
show the reaction diagram
Moorella sp.
-
isoform AdhA, 469%, isoform AdhB, 48% of the activity with acetaldehyde
-
-
r
isopentanol + NADP+
3-methylbutanal + NADPH + H+
show the reaction diagram
9% of activity with ethanol
-
-
r
isopropanol + NADP+
acetone + NADPH
show the reaction diagram
2% of activity with ethanol
-
-
r
L-arabitol + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
r
L-glyceraldehyde + NADPH
glycerol + NADP+
show the reaction diagram
L-gulonic acid + NADP+
D-glucuronic acid + NADPH
show the reaction diagram
L-gulonic acid + NADPH
D-glucuronic acid + NADP+
show the reaction diagram
L-sorbose + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
L-xylose + NADPH
? + NADP+
show the reaction diagram
lauryl aldehyde + NADPH
lauryl alcohol + NADP+
show the reaction diagram
m-chlorobenzaldehyde + NADPH + H+
m-chlorobenzyl alcohol + NADP+
show the reaction diagram
-
-
-
-
r
m-fluorobenzaldehyde + NADPH + H+
m-fluorobenzyl alcohol + NADP+
show the reaction diagram
m-methoxybenzaldehyde + NADPH + H+
m-methoxybenzyl alcohol + NADP+
show the reaction diagram
m-methylbenzaldehyde + NADPH
m-methylbenzyl alcohol + NADP+
show the reaction diagram
m-nitrobenzaldehyde + NADPH
m-nitrobenzylalcohol + NADP+
show the reaction diagram
malondialdehyde + NADPH
?
show the reaction diagram
-
-
-
-
r
menadione + NADPH
? + NADP+
show the reaction diagram
-
G2
-
-
?
meso-2,3-butanediol + NADP+
(S)-2-acetoin + NADPH + H+
show the reaction diagram
the enzyme shows higher oxidation activities on the (2R,3R)-(-)-2,3-butanediol and meso-2,3-butanediol than on the (2S,3S)-(+)-2,3-butanediol, indicating that the enzyme predominantly oxidizes the R-hydroxyl group of 2,3-butanediol and minorly functions on the S-hydroxyl group. When meso-2,3-butanediol is oxidized, (S)-2-acetoin is the predominant product, with an enantiomeric excess (ee) of 88%, while oxidation of meso-2,3-butanediol results in the production of (R)-2-acetoin with higher stereoselectivity (94% ee)
-
-
r
methanol + NADP+
formaldehyde + NADPH + H+
show the reaction diagram
-
-
-
-
r
methyl 4-bromo-3-oxobutanoate + NADPH + H+
methyl (S)-4-bromo-3-hydroxybutanoate + NADP+
show the reaction diagram
methyl acetoacetate + NADH + H+
methyl (R)-3-hydroxy-butanoate + NAD+
show the reaction diagram
-
-
-
-
?
methyl acetoacetate + NADPH + H+
methyl (R)-3-hydroxy-butanoate + NADP+
show the reaction diagram
-
-
-
-
?
methylglyoxal + NADPH
?
show the reaction diagram
methylglyoxal + NADPH
? + NADP+
show the reaction diagram
mevaldate + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
n-butanol + NADP+
butyraldehyde + NADPH
show the reaction diagram
n-butyraldehyde + NADPH
n-butanol + NADP+
show the reaction diagram
n-decanal + NADPH + H+
n-decanol + NADP+
show the reaction diagram
n-dodecanal + NADPH + H+
n-dodecanol + NADP+
show the reaction diagram
n-heptanal + NADPH
heptanol + NADP+
show the reaction diagram
n-heptanol + NADP+
n-heptanal + NADPH
show the reaction diagram
n-hexadecanal + NADPH + H+
n-hexadecanol + NADP+
show the reaction diagram
n-hexanol + NADP+
n-hexanal + NADPH
show the reaction diagram
n-octadecanal + NADPH + H+
n-octadecanol + NADP+
show the reaction diagram
-
-
-
-
r
n-octanal + NADPH + H+
n-octanol + NADP+
show the reaction diagram
n-propanol + NADP+
propionaldehyde + NADPH
show the reaction diagram
n-tetradecanal + NADPH + H+
n-tetradecanol + NADP+
show the reaction diagram
-
-
-
-
r
nonanal + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
o-fluorobenzaldehyde + NADPH + H+
o-fluorobenzyl alcohol + NADP+
show the reaction diagram
o-methylbenzaldehyde + NADPH
o-methylbenzyl alcohol + NADP+
show the reaction diagram
o-nitrobenzaldehyde + NADPH
o-nitrobenzylalcohol + NADP+
show the reaction diagram
octan-1-ol + NADP+
octanal + NADPH + H+
show the reaction diagram
octanal + NADPH + H+
1-octanol + NADP+
show the reaction diagram
octanal + NADPH + H+
octanol + NADP+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.2 mM NADPH, 42% relative activity with 0.1 mM or 80% relative activity with 1 mM substrate
-
-
r
octanaldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
octanol + NADP+
octanal + NADPH
show the reaction diagram
-
52% of activity with cinnamyl alcohol
-
-
r
octanol + NADP+
octanal + NADPH + H+
show the reaction diagram
octyl 4-chloro-3-oxobutanoate + NADPH
(R)-4-chloro-3-hydroxybutanoic acid ethyl ester + NADP+
show the reaction diagram
-
-
-
-
?
p-carboxybenzaldehyde + NADPH
p-carboxybenzyl alcohol + NADP+
show the reaction diagram
p-chlorobenzaldehyde + NADPH + H+
p-chlorobenzyl alcohol + NADP+
show the reaction diagram
p-cyanobenzaldehyde + NADPH
p-cyanobenzyl alcohol + NADP+
show the reaction diagram
p-fluorobenzaldehyde + NADPH + H+
p-fluorobenzyl alcohol + NADP+
show the reaction diagram
p-hydroxyphenylacetaldehyde + NADPH + H+
p-hydroxyphenylethanol + NADP+
show the reaction diagram
p-hydroxyphenylglycolaldehyde + NADPH
4-hydroxyphenylethylalcohol + NADP+
show the reaction diagram
p-methoxybenzaldehyde + NADPH + H+
p-methoxybenzyl alcohol + NADP+
show the reaction diagram
p-methylbenzaldehyde + NADPH
p-methylbenzyl alcohol + NADP+
show the reaction diagram
p-nitroacetophenone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
r
p-nitrobenzaldehyde + NADPH
p-nitrobenzylalcohol + NADP+
show the reaction diagram
p-tolualdehyde + NADPH
toluol + NADP+
show the reaction diagram
-
-
-
-
?
pent-1-en-3-ol + NADP+
pent-1-en-3-one + NADPH + H+
show the reaction diagram
-
good substrate
-
-
?
pentan-1-ol + NADP+
pentanal + NADPH + H+
show the reaction diagram
pentanal + NADPH
1-pentanol + NADP+
show the reaction diagram
pentanal + NADPH
pentanol + NADP+
show the reaction diagram
pentanal + NADPH + H+
pentan-1-ol + NADP+
show the reaction diagram
pentanal + NADPH + H+
pentanol + NADP+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.2 mM NADPH, 100% relative activity with 0.1 mM or 107% relative activity with 1 mM substrate
-
-
r
pentanol + NADP+
pentanal + NADPH
show the reaction diagram
pentanol + NADP+
pentanal + NADPH + H+
show the reaction diagram
phenylacetaldehyde + NADPH + H+
2-phenylethanol + NADP+
show the reaction diagram
phenylacetaldehyde + NADPH + H+
phenylethanol + NADP+
show the reaction diagram
phenylacetone + NADPH + H+
(S)-1-phenyl-2-propanol + NADP+
show the reaction diagram
-
-
-
-
r
phenylethanol + NADP+
? + NADPH + H+
show the reaction diagram
-
30 mM Tris-HCl (pH 8.0) in the presence of 0.5 mM NADP+, 15% relative activity with 1 mM or 24% relative activity with 10 mM substrate
-
-
?
phenylethanol + NADP+
phenylacetaldehyde + NADPH + H+
show the reaction diagram
-
15% activity with 1 mM phenylethanol, 24% activity with 10 mM phenylethanol
-
-
r
phenylethylamine + ?
?
show the reaction diagram
-
-
-
-
r
phenylglyoxal + NADPH
? + NADP+
show the reaction diagram
propan-1-ol + NADP+
propanal + NADPH + H+
show the reaction diagram
propan-2-ol + NADP+
acetone + NADPH + H+
show the reaction diagram
-
good substrate
-
-
?
propan-2-ol + NADP+
propanone + NADPH
show the reaction diagram
propanal + NADPH + H+
1-propanol + NADP+
show the reaction diagram
propanal + NADPH + H+
propan-1-ol + NADP+
show the reaction diagram
Moorella sp.
-
isoform AdhA, 50%, isoform AdhB, 62% of the activity with acetaldehyde
-
-
r
propanal + NADPH + H+
propanol + NADP+
show the reaction diagram
propanaldehyde + NADPH
propanol + NADP+
show the reaction diagram
-
-
-
-
r
propane-1,2-diol + NADP+
lactaldehyde + NADPH
show the reaction diagram
propanol + NADP+
propanal + NADPH
show the reaction diagram
propanol + NADP+
propanal + NADPH + H+
show the reaction diagram
-
21% activity with 1 mM propanol, 84% activity with 10 mM propanol
26% activity with 0.1 mM propanal, 87% activity with 1 mM propanal
-
r
propionaldehyde + NADPH
propanol + NADP+
show the reaction diagram
propionaldehyde + NADPH + H+
propanol + NADP+
show the reaction diagram
-
-
-
-
?
propiophenone + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
pyridoxal + NADPH
4,5-bis(hydroxymethyl)-2-methylpyridin-3-ol + NADP+
show the reaction diagram
-
-
-
-
?
pyruvaldehyde + NADP+
? + NADPH + H+
show the reaction diagram
-
-
-
-
r
pyruvaldehyde + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
pyruvaldehyde + NADPH + H+
lactaldehyde + NADP+
show the reaction diagram
pyruvate + NADPH
2-hydroxypropanoic acid + NADP+
show the reaction diagram
-
-
-
-
?
salicylaldehyde + NADPH
2-hydroxymethylphenol + NADP+
show the reaction diagram
-
-
-
-
?
salicylaldehyde + NADPH
salicylalcohol + NADP+
show the reaction diagram
1% of activity with acetaldehyde
-
-
r
salicylaldehyde + NADPH
salicylic alcohol + NADP+
show the reaction diagram
-
-
-
-
?
sinapaldehyde + NADPH + H+
sinapyl alcohol + NADP+
show the reaction diagram
succinic semialdehyde + NADPH + H+
4-hydroxybutyrate + NADP+
show the reaction diagram
tetradecanal + NADPH
tetradecanol
show the reaction diagram
-
-
-
-
r
trans-2-decenal + NADPH
trans-2-decen-1-ol + NADP+
show the reaction diagram
-
-
-
-
?
trans-2-hexenal + NADPH
trans-2-hexen-1-ol + NADP+
show the reaction diagram
-
-
-
-
?
trans-2-hexenol + NADP+
trans-2-hexenal + NADPH
show the reaction diagram
trans-2-nonenal + NADPH
trans-2-nonen-1-ol + NADP+
show the reaction diagram
-
33% activity compared to cinnamaldehyde
-
-
r
trans-2-nonenal + NADPH
trans-2-nonenol + NADP+
show the reaction diagram
-
39% of activity with cinnamaldehyde
-
-
r
trans-2-nonenaldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
trans-cinnamaldehyde + NADPH
cinnamyl alcohol + NADP+
show the reaction diagram
tridecanal + NADPH
tridecanol + NADP+
show the reaction diagram
-
-
-
-
r
Tris + NADP+
? + NADPH
show the reaction diagram
-
-
-
-
?
undecanal + NADPH
undecanol + NADP+
show the reaction diagram
-
-
-
-
?
valeraldehyde + NADPH + H+
? + NADP+
show the reaction diagram
-
-
-
-
?
vanillin + NADPH
4-hydroxy-3-methoxybenzyl alcohol + NADP+
show the reaction diagram
veratraldehyde + NADPH
3,4-dimethoxybenzyl alcohol + NADP+
show the reaction diagram
vitamin A aldehyde + NADPH
? + NADP+
show the reaction diagram
-
-
-
-
?
additional information
?
-