1.1.1.2: alcohol dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about alcohol dehydrogenase (NADP+), go to the full flat file.

Reaction

a primary alcohol
+
NADP+
=
an aldehyde
+
NADPH
+
H+

Synonyms

2° Adh, 3-DG-reducing enzyme, AAur_2040, ADH, ADH-1, ADH-2, ADH-I, ADH-II, ADH2, Adh319, ADH4, Adh6, AdhA, AdhB, AKR1A1, AKR1A4, alcohol dehydrogenase C, alcohol dehydrogenase [NADP(+)], Alcohol dehydrogenase [NADP+], aldehyde reductase, aldehyde reductase (NADPH2), aldehyde/ketone reductase, aldo-keto reductase, Aldo-keto reductase family 1 member A1, aldose reductase, ALDR, alipathic aldehyde reductase, ALR, ALR 1, ALR1, BdhA, bovine brain aldehyde reductase, D-glucuronate reductase, daunorubicin reductase, DRD, EhADH1, Gre2p, hexogenate dehydrogenase, high-Km aldehyde reductase, HvADH2, L-hexonate dehydrogenase, LB-RADH, LBADH, liver alcohol dehydrogenase, low-Km aldehyde reductase, mevaldate reductase, Mpd1, NADP(H)-dependent alcohol dehydrogenase, NADP-alcohol dehydrogenase, NADP-aldehyde reductase, NADP-dependent aldehyde reductase, NADP-linked aryl alcohol dehydrogenase, NADPH-aldehyde reductase, NADPH-cytochrome c reductase, NADPH-dependent aldehyde reductase, NADPH-dependent FALDR, NADPH-dependent fatty aldehyde reductase, NADPH-linked aldehyde reductase, nonspecific succinic semialdehyde reductase, Octopine dehydrogenase, putative iron alcohol dehydrogenase, PyAeADHII, rabbit kidney aldehyde-ketone reductase, RADH, ScADHVI, short-chain ADH, short-chain alcohol dehydrogenase, short-chain dehydrogenase/reductase, TBADH, TbADH1, Teth39_1597, Teth514_0564, TPN-L-hexonate dehydrogenase, TPNH-linked aldehyde reductase, TPNH-specific aldehyde reductase, triphosphopyridine nucleotide-linked aldehyde reductase, TsAdh319, Y63 protein, yeast alcohol dehydrogenase, YqhD

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.2 alcohol dehydrogenase (NADP+)

Molecular Weight

Molecular Weight on EC 1.1.1.2 - alcohol dehydrogenase (NADP+)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
20000
Thermococcus paravinellae
-
gel filtration
25000
-
gel filtration, ultracentrifugation, specific activity corresponding to molecular weight
25500
-
G2, gel filtration
25962
2 * 25962, calculated from sequence
26300
-
gel filtration
28500
-
gel filtration, reductase I
29000
-
gel filtration, high-Km reductase
30000 - 40000
-
-
31000
-
AR3, gel filtration
32600
-
1 * 32600, SDS-PAGE
32700
-
aldehyde reductase II, gel filtration
33500
-
1 * 33500, AR1, SDS-PAGE
33600
-
sedimentation analysis
34700
-
1 * 34700, AR3, SDS-PAGE
36200
-
gel filtration
36300
-
ultracentrifugation
36900
-
1 * 36900, SDS-PAGE
37100
-
calculated from amino acid sequence
38500
-
1 * 38500, SDS-PAGE
38800
-
gel filtration
39400
-
1 * 39400, SDS-PAGE
39500
-
AR2, SDS-PAGE
40200
-
SDS-PAGE
41000
-
SDS-PAGE
41700
-
1 * 41700, SDS-PAGE
42000
-
4 * 42000, 2° Adh, secondary alcohol dehydrogenase, SDS-PAGE
44500
-
4 * 44500, primary alcohol dehydrogenase, SDS-PAGE
44840
-
6 * 44840, mass spectrometric analysis
46000
Thermococcus paravinellae
-
4 * 46000, SDS-PAGE
46700
-
4 * 46700
50000 - 55000
gel filtration
56000
-
AR4, gel filtration
57000
-
1 * 57000, SDS-PAGE
68000
gel filtration
72000
-
gel filtration
74000
-
aldehyde reductase I, gel filtration
80000
-
gel filtration
80500
-
pH-dependent enzyme structure, pH 7.5
81000
-
gel filtration
90000
-
-
130000
-
gel filtration
135000
gel filtration
140000
-
gel filtration; SDS-PAGE
150000
-
gel filtration
158000
-
gel filtration
160000
170000
-
1° Adh, primary-alcohol dehydrogenase, gel filtration
172000
-
secondary alcohol dehydrogenase, gel filtration
176000
recombinant enzyme, gel filtration
179200
calculated from amino acid sequence
180000
SDS-PAGE
182000
native enzyme, gel filtration
184000
-
primary alcohol dehydrogenase, gel filtration
197000
-
pH-dependent enzyme structure, pH 10.5
200000
-
gel filtration
270000
-
gel filtration