1.1.1.197: 15-hydroxyprostaglandin dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about 15-hydroxyprostaglandin dehydrogenase (NADP+), go to the full flat file.

Reaction

(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate
+
NADP+
=
(13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate
+
NADPH
+
H+

Synonyms

9-ketoprostaglandin reductase, carbonyl reductase, NADP-dependent 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostglandin dehydrogenase, NADP-specific 15-hydroxyprostaglandin dehydrogenase, prostaglandin 9-ketoreductase, prostaglandin E 9-ketoreductase, type II 15-hydroxyprostaglandin dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)

Sequence

Sequence on EC 1.1.1.197 - 15-hydroxyprostaglandin dehydrogenase (NADP+)

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UNIPROT
ENTRY NAME
ORGANISM
NO. OF AA
MOLECULAR WEIGHT[Da]
SOURCE
Sequence
CBR1_MACFA
277
30473
Swiss-Prot
CBR1_PONAB
277
30391
Swiss-Prot
CBR1_RAT
277
30578
Swiss-Prot
CBR1_HUMAN
277
30375
Swiss-Prot
CBR1_BOVIN
277
30533
Swiss-Prot
CBR1_MOUSE
277
30641
Swiss-Prot
CBR1_RABIT
277
30452
Swiss-Prot
CBR1_PIG
289
31693
Swiss-Prot
A0A0C1C1D0_9CHLA
241
26248
TrEMBL
A0A0B8NGM8_9NOCA
281
29530
TrEMBL
A0A0B2RJ58_GLYSO
303
33173
TrEMBL
F8L0N3_PARAV
Parachlamydia acanthamoebae (strain UV7)
231
24993
TrEMBL
A0A0B2PAC8_GLYSO
296
31916
TrEMBL
G0QZX6_ICHMG
Ichthyophthirius multifiliis (strain G5)
223
26040
TrEMBL
B6R2U0_9RHOB
219
23470
TrEMBL
A0A0B2RF98_GLYSO
303
33187
TrEMBL
G0QL08_ICHMG
Ichthyophthirius multifiliis (strain G5)
272
31160
TrEMBL
Q09E76_STIAD
Stigmatella aurantiaca (strain DW4/3-1)
234
26134
TrEMBL
Q097P7_STIAD
Stigmatella aurantiaca (strain DW4/3-1)
234
25733
TrEMBL
A0A0B2RU65_GLYSO
77
8367
TrEMBL