1.1.1.197: 15-hydroxyprostaglandin dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about 15-hydroxyprostaglandin dehydrogenase (NADP+), go to the full flat file.

Reaction

(13E)-(15S)-11alpha,15-dihydroxy-9-oxoprost-13-enoate
+
NADP+
=
(13E)-11alpha-hydroxy-9,15-dioxoprost-13-enoate
+
NADPH
+
H+

Synonyms

9-ketoprostaglandin reductase, carbonyl reductase, NADP-dependent 15-hydroxyprostaglandin dehydrogenase, NADP-linked 15-hydroxyprostglandin dehydrogenase, NADP-specific 15-hydroxyprostaglandin dehydrogenase, prostaglandin 9-ketoreductase, prostaglandin E 9-ketoreductase, type II 15-hydroxyprostaglandin dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.197 15-hydroxyprostaglandin dehydrogenase (NADP+)

Purification

Purification on EC 1.1.1.197 - 15-hydroxyprostaglandin dehydrogenase (NADP+)

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Purification/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
partial
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