1.1.1.192: long-chain-alcohol dehydrogenase

This is an abbreviated version, for detailed information about long-chain-alcohol dehydrogenase, go to the full flat file.

Reaction

a long-chain alcohol
+ 2 NAD+ +
H2O
=
a long-chain carboxylate
+ 2 NADH + 2 H+

Synonyms

ADH1, ADH2, dehydrogenase, long-chain alcohol, fatty alcohol oxidoreductase, long-chain alcohol dehydrogenase, long-chain alkyl alcohol dehydrogenase, long-chain dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.192 long-chain-alcohol dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.192 - long-chain-alcohol dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(2S)-5-hydroxy-2-aminovaleric acid + NAD+ + H2O
(2S)-2-amino-5-oxopentanoate + NADH
show the reaction diagram
-
no activity with the (2R)-isomer
-
-
?
(2S,4S)-5-hydroxyleucine + NAD+ + H2O
(4S)-5-oxo-L-leucine + NADH
show the reaction diagram
1,3-propanediol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
show the reaction diagram
1-decanol + 2 NAD+ + H2O
decanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-dodecanol + 2 NAD+ + H2O
dodecanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-eicosanol + 2 NAD+ + H2O
eicosanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-hexadecanol + 2 NAD+ + H2O
hexadecanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-octacosanol + 2 NAD+ + H2O
octacosanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-octadecanol + 2 NAD+ + H2O
octadecanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-octanol + 2 NAD+ + H2O
octanoic acid + 2 NADH + 2 H+
show the reaction diagram
-
-
-
r
1-octanol + 2 NADP+ + H2O
octanoic acid + 2 NADPH + 2 H+
show the reaction diagram
-
-
-
r
1-tetracosanol + 2 NAD+ + H2O
tetracosanoic acid + 2 NADH + 2 H+
show the reaction diagram
1-tetradecanol + 2 NAD+ + H2O
tetradecanoic acid + 2 NADH + 2 H+
show the reaction diagram
12-hydroxydodecanoic acid + NAD+ + H2O
? + NADH
show the reaction diagram
-
-
-
-
?
decanal + NAD+ + H+
decanoic acid + NADH
show the reaction diagram
about 10% of the activity with 1-octanol
-
-
r
dodecanal + NAD+ + H+
dodecanoic acid + NADH
show the reaction diagram
about 10% of the activity with 1-octanol
-
-
r
ethanol + NAD+ + H2O
ethanal + NADH
show the reaction diagram
-
-
-
-
?
glycerol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
show the reaction diagram
about 45% of the activity with ethanol
-
-
r
hexadecanol + NAD+ + H2O
hexadecanal + NADH
show the reaction diagram
-
-
-
-
?
isopropanol + 2 NAD+ + H2O
? + 2 NADH + 2 H+
show the reaction diagram
about 15% of the activity with 1-octanol
-
-
r
long-chain alcohol + NAD+ + H2O
long-chain carboxylate + NADH
show the reaction diagram
n-butanol + NAD+ + H2O
n-butanal + NADH
show the reaction diagram
n-decanol + NAD+ + H2O
n-decanal + NADH
show the reaction diagram
-
-
-
-
r
n-heptanol + NAD+ + H2O
n-heptanal + NADH
show the reaction diagram
-
-
-
-
?
n-hexanol + NAD+ + H2O
n-hexanal + NADH
show the reaction diagram
n-nonanol + NAD+ + H2O
n-nonanal + NADH
show the reaction diagram
-
-
-
-
?
n-octanol + NAD+ + H2O
n-octanal + NADH
show the reaction diagram
-
-
-
-
?
n-pentanol + NAD+ + H2O
n-pentanal + NADH
show the reaction diagram
n-propanol + NAD+ + H2O
n-propanal + NADH
show the reaction diagram
octanal + NAD+ + H2O
octanoic acid + NADH + H+
show the reaction diagram
-
-
-
r
additional information
?
-