1.1.1.192: long-chain-alcohol dehydrogenase

This is an abbreviated version, for detailed information about long-chain-alcohol dehydrogenase, go to the full flat file.

Reaction

a long-chain alcohol
+ 2 NAD+ +
H2O
=
a long-chain carboxylate
+ 2 NADH + 2 H+

Synonyms

ADH1, ADH2, dehydrogenase, long-chain alcohol, fatty alcohol oxidoreductase, long-chain alcohol dehydrogenase, long-chain alkyl alcohol dehydrogenase, long-chain dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.192 long-chain-alcohol dehydrogenase

KM Value

KM Value on EC 1.1.1.192 - long-chain-alcohol dehydrogenase

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KM VALUE [mM]
SUBSTRATE
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
1.2
(2S)-5-hydroxy-2-aminovaleric acid
-
pH 10.0, 42°C, recombinant enzyme
0.24
(2S,4S)-5-hydroxyleucine
-
pH 10.0, 42°C, recombinant enzyme
3.4
1-Hexanol
-
-
1.2 - 3.88
1-Octanol
26.5
1-Pentanol
-
-
324
1-propanol
-
-
1.7
12-Hydroxydodecanoic acid
-
-
0.00067
hexadecanol
-
-
0.044
n-butanol
-
-
0.095
n-decanal
-
-
0.23
n-decanol
-
-
0.26
n-Heptanol
-
-
0.14
n-Hexanol
-
-
0.36
n-nonanol
-
-
0.34
n-Octanol
-
-
0.18
n-Pentanol
-
-
0.053
n-Propanol
-
-
0.31 - 1.44
NAD+
0.17
NADH
-
-
2.4
NADP+
cosubstrate 1-octanol, pH 8.0, 60°C
0.84
NADPH
cosubstrate octanal, pH 8.0, 60°C
1.15
octanal
cosubstrate NADPH, pH 8.0, 60°C