1.1.1.184: carbonyl reductase (NADPH)

This is an abbreviated version, for detailed information about carbonyl reductase (NADPH), go to the full flat file.

Reaction

R-CHOH-R'
+
NADP+
=
R-CO-R'
+
NADPH
+
H+

Synonyms

15-hydroxyprostaglandin dehydrogenase [NADP+], 2,5-diketo-D-gluconic acid reductase, Adipocyte P27 protein, aldehyde reductase 1, aldehyde reductase I, aldo-keto reductase, ALR3, AP27, carbonyl reductase, carbonyl reductase (NADPH), carbonyl reductase 1, carbonyl reductase 3, carbonyl reductase S1, CBR, CBR 1, CBR 3, CBR1, CBR3, CHCR, CHCR1, CHCR2, CHCR3, CR, CSCR1, Gox0644, Gox1615, ketoreductase, KLCR1, KR, LCR, microsomal carbonyl reductase, More, NADP+-dependent ADH, NADPH-carbonyl reductase, NADPH-dependent carbonyl reductase, NADPH-dependent carbonyl reductase S1, NCCR, nonspecific NADPH-dependent carbonyl reductase, peroxisomal-type carbonyl reductase, PHCR, prostaglandin 9-ketoreductase, Prostaglandin-E2 9-reductase, PTCR, R-specific carbonyl reductase, reductase S1, reductase, carbonyl, RLCR, SCR, SDR21C1, secondary-alcohol: NADP+-oxidoreductase, short-chain (S)-1-phenyl-1,2-ethanediol dehydrogenase, short-chain carbonyl reductase, sniffer, SSCR, Tm1743, Tm_1743, xenobiotic carbonyl reductase, xenobiotic ketone reductase, YtbE

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.184 carbonyl reductase (NADPH)

Molecular Weight

Molecular Weight on EC 1.1.1.184 - carbonyl reductase (NADPH)

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MOLECULAR WEIGHT
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
24800
Cylindrocarpon sclerotigenum
-
x * 24800, SDS-PAGE
28000 - 32000
-
gel filtration, SDS-PAGE
30100
-
sequence analysis
31600
2 * 31600, SDS-PAGE; 2 * 31600, SDS-PAGE
33000
-
rat, different enzyme forms from testis and vas deferens, SDS-PAGE
33700
gel filtration
33950
mass spectrometry, His-tagged CHCR2
34040
sequence analysis, His-tagged CHCR1
34080
sequence analysis, His-tagged CHCR2
34300
mass spectrometry, His-tagged CHCR3
34430
sequence analysis, His-tagged CHCR3
35032
x * 35000, SDS-PAGE, x * 35032, calculated
37500
-
1 * 37500, enzyme form CR1, SDS-PAGE
37533
1 * 40000, SDS-PAGE, 1 * 37533, calculated
38000
1 * 38000, SDS-PAGE
42000 - 48000
Candida macedoniensis
-
gel filtration, SDS-PAGE
44000
-
4 * 44000, SDS-PAGE
45500
-
gel filtration
46000
-
1 * 46000, SDS-PAGE
48000
-
gel filtration, enzyme form CR1
58000
-
gel filtration, mutant V270D
67000
-
2 * 67000, SDS-PAGE
67400
-
gel filtration
68000
Cylindrocarpon sclerotigenum
-
gel filtration
76000
-
gel filtration
86000
-
gel filtration
90000
-
gel filtration
100000
103000
-
gel filtration, SDS-PAGE
110000
112000
-
analytic ultracentrifugation, wild-type
115000
-
gel filtration, enzyme form CR2
135000
-
gel filtration
175000
-
gel filtration
190000
-
x * 190000, SDS-PAGE
additional information