1.1.1.18: inositol 2-dehydrogenase

This is an abbreviated version, for detailed information about inositol 2-dehydrogenase, go to the full flat file.

Reaction

myo-inositol
+
NAD+
=
2,4,6/3,5-pentahydroxycyclohexanone
+
NADH
+
H+

Synonyms

BsIDH, IDH, inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, inositol dehydrogenase, iolG, MI dehydrogenase, More, myo-inositol 2-dehydrogenase, myo-inositol dehydrogenase, myo-inositol:NAD2 oxidoreductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.18 inositol 2-dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.18 - inositol 2-dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
(1S,2S,3R,4S,5S)-5-(allyloxy)cyclohexane-1,2,3,4-tetrol + NAD+
?
show the reaction diagram
-
-
-
-
?
(1S,2S,3R,4S,5S)-5-(benzyloxy)cyclohexane-1,2,3,4-tetrol + NAD+
?
show the reaction diagram
-
-
-
-
?
(1S,2S,3R,4S,5S)-5-methoxycyclohexane-1,2,3,4-tetrol + NAD+
?
show the reaction diagram
-
-
-
-
?
1-oxo-D-chiro-inositol + NADH + H+
D-chiro-inositol + NAD+
show the reaction diagram
4-([[(1S,2S,3R,4S,5S)-2,3,4,5-tetrahydroxycyclohexyl]oxy]methyl)benzoic acid + NAD+
?
show the reaction diagram
-
-
-
-
?
4-methylbenzenesulfonyl-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-((1S)-10-camphor-sulfonyl)-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-((4-methyloxycarbonyl)-benzyl)-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-(4-carboxybenzyl)-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-(trans-cinnamoyl)-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-allyl-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-alpha-D-glucopyranosyl-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-benzyl-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-methyl-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-[(2-methylphenyl)methyl]-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
4-O-[(3-methylphenyl)methyl]-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
alpha-D-glucopyranose + NAD+
D-gluconate + NADH
show the reaction diagram
-
4fold lower activity compared to myo-inositol as substrate, does not act with the beta-anomer
-
?
alpha-D-glucopyranosyl-(1,6)-myo-inositol + NAD+
?
show the reaction diagram
-
-
-
-
?
D-2,3-diketo-4-deoxy-epi-inositol + NADH
ketodeoxyinositol + NAD+
show the reaction diagram
-
-
-
?
D-chiro-inositol + NAD+
? + NADH
show the reaction diagram
-
19% of the activity with myo-inositol
-
-
?
D-glucose + NAD+
D-gluconate + NADH
show the reaction diagram
D-xylose + NAD+
? + NADH
show the reaction diagram
epi-inositol + NAD+
? + NADH
show the reaction diagram
-
4% of the activity with myo-inositol
-
-
?
epi-inositol + NAD+
epi-inosose + NADH
show the reaction diagram
-
5% of the activity compared to myo-inositol as substrate, conversion of epi-inosose 5% of the activity compared to scyllo-inosose as substrate
-
r
melibiose + NAD+
?
show the reaction diagram
-
-
-
-
?
methyl 4-([[(1S,2S,3R,4S,5S)-2,3,4,5-tetrahydroxycyclohexyl]oxy]methyl)benzoate + NAD+
?
show the reaction diagram
-
-
-
-
?
myo-inositol + 2,6-dichlorophenolindophenol
2,4,6/3,5-pentahydroxycyclohexanone + reduced 2,6-dichlorophenolindophenol
show the reaction diagram
-
-
-
?
myo-inositol + NAD+
2,3,4,5,6-pentahydroxycyclohexanone + NADH
show the reaction diagram
-
-
-
-
r
myo-inositol + NAD+
2,3,4,5,6-pentahydroxycyclohexanone + NADH + H+
show the reaction diagram
myo-inositol + NAD+
2,4,6/3,5-pentahydroxycyclohexanone + NADH
show the reaction diagram
myo-inositol + NAD+
scyllo-inosose + NADH
show the reaction diagram
myo-inositol + NAD+
scyllo-inosose + NADH + H+
show the reaction diagram
pinitol + NADH + H+
?
show the reaction diagram
scyllo-inositol + NAD+
scyllo-inosose + NADH
show the reaction diagram
-
5% of the activity compared to myo-inositol as substrate
-
?
[(4-methylphenyl)methyl]-myo-inositol + NAD+
? + NADH + H+
show the reaction diagram
-
-
-
-
?
additional information
?
-