1.1.1.18: inositol 2-dehydrogenase

This is an abbreviated version, for detailed information about inositol 2-dehydrogenase, go to the full flat file.

Reaction

myo-inositol
+
NAD+
=
2,4,6/3,5-pentahydroxycyclohexanone
+
NADH
+
H+

Synonyms

BsIDH, IDH, inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase, inositol dehydrogenase, iolG, MI dehydrogenase, More, myo-inositol 2-dehydrogenase, myo-inositol dehydrogenase, myo-inositol:NAD2 oxidoreductase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.18 inositol 2-dehydrogenase

Cloned

Cloned on EC 1.1.1.18 - inositol 2-dehydrogenase

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Cloned/COMMENTARY
ORGANISM
UNIPROT
LITERATURE
expression in Escherichia coli
-
expression of His-tagged native and selenomethionine-labeled enzyme in Escherichia coli
-
gene iolG, encoded and transcribed in the iolTABCDG1G2EJK operon, DNA and amino acid sequence determination and analysis, genetic organization, genes encoded in the iolTABCDG1G2EJK operon transcribe a complete MI catabolic pathway, transcriptional regulation pattern, phalogenetic analysis, overview
-
gene iolG, expression analysis
-
organization of iol genes, three paralogous iol genes GK1897, GK1898, and GK1899 located in tandem within a large gene cluster, determination of the transcription start site, individual expression as His6-tagged proteins in Escherichia coli strain BL21(DE3)
-