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1.1.1.178: 3-hydroxy-2-methylbutyryl-CoA dehydrogenase

This is an abbreviated version!
For detailed information about 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, go to the full flat file.

Word Map on EC 1.1.1.178

Reaction

(2S,3S)-3-hydroxy-2-methylbutanoyl-CoA
+
NAD+
=
2-methylacetoacetyl-CoA
+
NADH
+
H+

Synonyms

17beta-HSD10, 17beta-hydroxysteroid dehydrogenase type 10, 2-methyl-3-hydroxy-butyryl CoA dehydrogenase, 2-methyl-3-hydroxybutyryl coenzyme A dehydrogenase, 2-methyl-3-hydroxybutyryl-CoA dehydrogenase, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase, 3-hydroxyacyl-CoA dehydrogenase type II, dehydrogenase, 2-methyl-3-hydroxybutyryl coenzyme A, HADII, HSD10, MHBD, SCHAD, short chain 3-hydroxyacyl-CoA dehydrogenase, short-chain L-3-hydroxy-2-methylacyl-CoA dehydrogenase, type II 3-hydroxyacyl-CoA dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.178 3-hydroxy-2-methylbutyryl-CoA dehydrogenase

Substrates Products

Substrates Products on EC 1.1.1.178 - 3-hydroxy-2-methylbutyryl-CoA dehydrogenase

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
2-hydroxy-3-methylpentanoyl-CoA + NAD+
3-methyl-2-oxopentanoyl-CoA + NADH
show the reaction diagram
2-methyl-3-hydroxybutyryl-CoA
2-methyl-acetoacetyl-CoA
show the reaction diagram
-
among the best substrates
-
-
?
2-methyl-3-hydroxybutyryl-CoA + NAD+
2-methylacetoacetyl-CoA + NADH
show the reaction diagram
2-methyl-3-hydroxybutyryl-CoA + NAD+
2-methylacetoacetyl-CoA + NADH + H+
show the reaction diagram
-
-
-
-
?
3-hydroxybutyryl-CoA + NAD+
acetoacetyl-CoA + NADH
show the reaction diagram
additional information
?
-