22.214.171.124: 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
This is an abbreviated version, for detailed information about 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating),
go to the full flat file. Reaction
a 3beta-hydroxysteroid-4alpha-carboxylate =
a 3-oxosteroid +
CO2 NAD(P)H Synonyms
3beta-hydroxy-4alpha-methylcholestenecarboxylate 3-dehydrogenase (decarboxylating), 3beta-hydroxy-4beta-methylcholestenoate dehydrogenase, 4alpha-carboxylic acid decarboxylase, C-3 sterol dehydrogenase(C-4 decarboxylase), NSDHL, sterol 4alpha-carboxylic decarboxylase, sterol-4alpha-carboxylate 3-dehydrogenase
Systematic Name on EC 126.96.36.199 - 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating)
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3beta-hydroxysteroid-4alpha-carboxylate:NAD(P)+ 3-oxidoreductase (decarboxylating)
The enzyme catalyses the decarboxylation of the C-4 carbon and the dehydrogenation of a 3beta hydroxyl at the C-3 carbon of 3beta-hydroxysteroid-4alpha-carboxylates. It is involved in zymosterol and cholesterol biosynthesis.