1.1.1.17: mannitol-1-phosphate 5-dehydrogenase

This is an abbreviated version, for detailed information about mannitol-1-phosphate 5-dehydrogenase, go to the full flat file.

Reaction

D-mannitol 1-phosphate
+
NAD+
=
D-fructose 6-phosphate
+
NADH
+
H+

Synonyms

BbMPD, D-mannitol-1-phosphate dehydrogenase, dehydrogenase, mannitol 1-phosphate, fructose 6-phosphate reductase, hexose reductase, long-chain mannitol-1-phosphate 5-dehydrogenase, long-chain mannitol-1-phosphate dehydrogenase, M1PDH, M1PDH1, M1PDH2, M1PDH3, mannitol 1-phosphate 5-dehydrogenase, mannitol 1-phosphate dehydrogenase, mannitol-1-phosphate dehydrogenase, MPD, MpdA, MPDH, MtlD, NAD+-dependent mannitol-1-phosphate dehydrogenase, NADH-dependent mannitol-1-phosphate 5-dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.17 mannitol-1-phosphate 5-dehydrogenase

Reference

Reference on EC 1.1.1.17 - mannitol-1-phosphate 5-dehydrogenase

Please use the Reference Search for a specific query.
Please wait a moment until all data is loaded. This message will disappear when all data is loaded.
REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Schmatz D.M.; Baginsky W.F.; Turner, M.J.
Evidence for and characterization of a mannitol cycle in Eimeria tenella
Mol. Biochem. Parasitol.
32
263-270
1989
Eimeria tenella, Eimeria tenella (O96437)
Manually annotated by BRENDA team
Liss, M.; Horwitz, S.B.; Kaplan, N.O.
D-Mannitol 1-phosphate dehydrogenase and D-sorbitol 6-phosphate dehydrogenase in Aerobacter aerogenes
J. Biol. Chem.
237
1342-1350
1962
Enterobacter aerogenes
Manually annotated by BRENDA team
Novotny, M.J.; Reizer, J.; Esch, F.; Saier, M.H.
Purification and properties of D-mannitol-1-phosphate dehydrogenase and D-glucitol-6-phosphate dehydrogenase from Escherichia coli
J. Bacteriol.
159
986-990
1984
Escherichia coli
Manually annotated by BRENDA team
Mehta, R.J.; Fare, L.R.; Shearer, M.E.; Nash, C.H.
Mannitol oxidation in two Micromonospora isolates and in representative species of other actinomycetes
Appl. Environ. Microbiol.
33
1013-1015
1977
Amycolatopsis lactamdurans, Micromonospora sp., no activity in Actinoplanes missouriensis, no activity in Mycobacterium smegmatis, no activity in Nocardia erythropolis
Manually annotated by BRENDA team
Otte, S.; Lengeler, J.W.
The mtl genes and the mannitol-1-phosphate dehydrogenase from Klebsiella pneumoniae KAY2026
FEMS Microbiol. Lett.
194
221-227
2001
Klebsiella pneumoniae
Manually annotated by BRENDA team
Survarna, K.; Bartiss, A.; Wong, B.
Mannitol-1-phosphate dehydrogenase from Cryptococcus neoformans is a zinc-containing long-chain alcohol/polyol dehydrogenase
Microbiology
146
2705-2713
2000
Cryptococcus neoformans
Manually annotated by BRENDA team
Henstra, S.A.; Tolner, B.; Ten Hoeve Duurkens, R.H.; Konings, W.N.; Robillard, G.T.
Cloning, expression, and isolation of the mannitol transport protein from the thermophilic bacterium Bacillus stearothermophilus
J. Bacteriol.
178
5586-5591
1996
Geobacillus stearothermophilus
Manually annotated by BRENDA team
Singh, S.P.; Rogers, P.J.
Isolation and characterization of mannitol-1-phosphate dehydrogenase from Brochothrix thermosphacta
J. Gen. Appl. Microbiol.
39
327-337
1993
Brochothrix thermosphacta
-
Manually annotated by BRENDA team
Honeyman, A.L.; Curtiss III, R.
Isolation, characterization, and nucleotide sequence of the Streptococcus mutans mannitol-phosphate dehydrogenase gene and the mannitol-specific factor III gene of the phosphoenolpyruvate phosphotransferase system
Infect. Immun.
60
3369-3375
1992
Streptococcus mutans
Manually annotated by BRENDA team
Fischer, R.; von Strandmann, R.P.; Hengstenberg, W.
Mannitol-specific phosphoenolpyruvate-dependent phosphotransferase system of Enterococcus faecalis: Molecular cloning and nucleotide sequences of the enzyme III Mtl gene and the mannitol-1-phosphate dehydrogenase gene, expression in Escherichia coli, and comparison of the gene products with similar enzymes
J. Bacteriol.
173
3709-3715
1991
Enterococcus faecalis, Staphylococcus carnosus
Manually annotated by BRENDA team
Chase, T.
Mannitol-1-phosphate dehydrogenase of Escherichia coli
Biochem. J.
239
435-443
1986
Escherichia coli
Manually annotated by BRENDA team
Foreman, J.E.; Niehaus, W.G.
Zn2+-induced cooperativity of mannitol-1-phosphate dehydrogenase from Aspergillus parasiticus
J. Biol. Chem.
260
10019-10022
1985
Aspergillus niger, Aspergillus parasiticus
Manually annotated by BRENDA team
Kiser, R.C.; Niehaus, W.G.
Purification and kinetic characterization of mannitol-1-phosphate dehydrogenase from Aspergillus niger
Arch. Biochem. Biophys.
211
613-621
1981
Aspergillus niger
Manually annotated by BRENDA team
Brown, A.T.; Bowles, R.D.
Polyol metabolism by a caries-conductive Streptococcus: Purification and properties of a nicotinamide adenine dinucleotide-dependent mannitol-1-phosphate dehydrogenase
Infect. Immun.
16
163-173
1977
Streptococcus mutans
Manually annotated by BRENDA team
Hankinson, O.; Cove, D.J.
Regulation of mannitol-1-phosphate dehydrogenase in Aspergillus nidulans
Can. J. Microbiol.
21
99-101
1975
Aspergillus nidulans
Manually annotated by BRENDA team
Wolff, J.B.; Kaplan, N.O.
D-Mannitol-1-phosphate dehydrogenase from E. coli
Methods Enzymol.
1
346-348
1955
Escherichia coli
-
Manually annotated by BRENDA team
Wisselink, H.W.; Mars, A.E.; van der Meer, P.; Eggink, G.; Hugenholtz, J.
Metabolic engineering of mannitol production in Lactococcus lactis: influence of overexpression of mannitol 1-phosphate dehydrogenase in different genetic backgrounds
Appl. Environ. Microbiol.
70
4286-4292
2004
Lactococcus plantarum
Manually annotated by BRENDA team
Watanabe, S.; Hamano, M.; Kakeshita, H.; Bunai, K.; Tojo, S.; Yamaguchi, H.; Fujita, Y.; Wong, S.L.; Yamane, K.
Mannitol-1-phosphate dehydrogenase (MtlD) is required for mannitol and glucitol assimilation in Bacillus subtilis: possible cooperation of mtl and gut operons
J. Bacteriol.
185
4816-4824
2003
Bacillus subtilis
Manually annotated by BRENDA team
Iwamoto, K.; Kawanobe, H.; Ikawa, T.; Shiraiwa, Y.
Characterization of salt-regulated mannitol-1-phosphate dehydrogenase in the red alga Caloglossa continua
Plant Physiol.
133
893-900
2003
Caloglossa continua
Manually annotated by BRENDA team
Chiang, Y.; Stushnoff, C.; McSay, A.E.; Jones, M.L.; Bohnert, H.J.
Overexpression of mannitol-1-phosphate dehydrogenase increases mannitol accumulation and adds protection against chilling injury in Petunia
J. Am. Soc. Hort. Sci.
130
605-610
2005
Escherichia coli
-
Manually annotated by BRENDA team
Solomon, P.S.; Tan, K.C.; Oliver, R.P.
Mannitol 1-phosphate metabolism is required for sporulation in planta of the wheat pathogen Stagonospora nodorum
Mol. Plant Microbe Interact.
18
110-115
2005
Parastagonospora nodorum, Parastagonospora nodorum (Q0U6E8)
Manually annotated by BRENDA team
Tang, W.; Peng, X.; Newton, R.J.
Enhanced tolerance to salt stress in transgenic loblolly pine simultaneously expressing two genes encoding mannitol-1-phosphate dehydrogenase and glucitol-6-phosphate dehydrogenase
Plant Physiol. Biochem.
43
139-146
2005
Agrobacterium tumefaciens
Manually annotated by BRENDA team
Ladero, V.; Ramos, A.; Wiersma, A.; Goffin, P.; Schanck, A.; Kleerebezem, M.; Hugenholtz, J.; Smid, E.J.; Hols, P.
High-level production of the low-calorie sugar sorbitol by Lactobacillus plantarum through metabolic engineering
Appl. Environ. Microbiol.
73
1864-1872
2007
Lactobacillus plantarum
Manually annotated by BRENDA team
Krahulec, S.; Armao, G.C.; Weber, H.; Klimacek, M.; Nidetzky, B.
Characterization of recombinant Aspergillus fumigatus mannitol-1-phosphate 5-dehydrogenase and its application for the stereoselective synthesis of protio and deuterio forms of D-mannitol 1-phosphate
Carbohydr. Res.
343
1414-1423
2008
Aspergillus fumigatus, Aspergillus fumigatus (Q4X1A4)
Manually annotated by BRENDA team
Velez, H.; Glassbrook, N.J.; Daub, M.E.
Mannitol biosynthesis is required for plant pathogenicity by Alternaria alternata
FEMS Microbiol. Lett.
285
122-129
2008
Alternaria alternata, Alternaria alternata A5
Manually annotated by BRENDA team
Pujni, D.; Chaudhary, A.; Rajam, M.V.
Increased tolerance to salinity and drought in transgenic indica rice by mannitol accumulation
J. Plant Biochem. Biotechnol.
16
1-7
2007
Escherichia coli
-
Manually annotated by BRENDA team
Krahulec, S.; Armao, G.C.; Bubner, P.; Klimacek, M.; Nidetzky, B.
Polyol-specific long-chain dehydrogenases/reductases of mannitol metabolism in Aspergillus fumigatus: biochemical characterization and pH studies of mannitol 2-dehydrogenase and mannitol-1-phosphate 5-dehydrogenase
Chem. Biol. Interact.
178
274-282
2009
Aspergillus fumigatus
Manually annotated by BRENDA team
Wang, Z.L.; Ying, S.H.; Feng, M.G.
Gene cloning and catalysis features of a new mannitol-1-phosphate dehydrogenase (BbMPD) from Beauveria bassiana
Carbohydr. Res.
345
50-54
2010
Beauveria bassiana, Beauveria bassiana (C7FDI4)
Manually annotated by BRENDA team
Aguilar-Osorio, G.; Vankuyk, P.A.; Seiboth, B.; Blom, D.; Solomon, P.S.; Vinck, A.; Kindt, F.; Woesten, H.A.; de Vries, R.P.
Spatial and developmental differentiation of mannitol dehydrogenase and mannitol-1-phosphate dehydrogenase in Aspergillus niger
Eukaryot. Cell
9
1398-1402
2010
Aspergillus niger
Manually annotated by BRENDA team
Sand, M.; Mingote, A.I.; Santos, H.; Mueller, V.; Averhoff, B.
Mannitol, a compatible solute synthesized by Acinetobacter baylyi in a two-step pathway including a salt-induced and salt-dependent mannitol-1-phosphate dehydrogenase
Environ. Microbiol.
15
2187-2197
2013
Acinetobacter baylyi
Manually annotated by BRENDA team
Krahulec, S.; Armao, G.C.; Klimacek, M.; Nidetzky, B.
Enzymes of mannitol metabolism in the human pathogenic fungus Aspergillus fumigatus--kinetic properties of mannitol-1-phosphate 5-dehydrogenase and mannitol 2-dehydrogenase, and their physiological implications
FEBS J.
278
1264-1276
2011
Aspergillus fumigatus
Manually annotated by BRENDA team
Rambhatla, P.; Kumar, S.; Floyd, J.T.; Varela, M.F.
Molecular cloning and characterization of mannitol-1-phosphate dehydrogenase from Vibrio cholerae
J. Microbiol. Biotechnol.
21
914-920
2011
Vibrio cholerae, Vibrio cholerae O395
Manually annotated by BRENDA team
Rousvoal, S.; Groisillier, A.; Dittami, S.; Michel, G.; Boyen, C.; Tonon, T.
Mannitol-1-phosphate dehydrogenase activity in Ectocarpus siliculosus, a key role for mannitol synthesis in brown algae
Planta
233
261-273
2011
Ectocarpus siliculosus (D7FMJ8), Ectocarpus siliculosus (D7G793), Ectocarpus siliculosus (D8LI09), Ectocarpus siliculosus, Ectocarpus siliculosus 32, CCAP 1310/4 (D7FMJ8), Ectocarpus siliculosus 32, CCAP 1310/4 (D7G793), Ectocarpus siliculosus 32, CCAP 1310/4 (D8LI09)
Manually annotated by BRENDA team