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1.1.1.17: mannitol-1-phosphate 5-dehydrogenase
This is an abbreviated version, for detailed information about mannitol-1-phosphate 5-dehydrogenase, go to the full flat file.
Reaction
Synonyms
BbMPD, D-mannitol-1-phosphate dehydrogenase, dehydrogenase, mannitol 1-phosphate, EsM1PDH1, EsM1PDH2, EsM1PDH3, fructose 6-phosphate reductase, hexose reductase, long-chain mannitol-1-phosphate 5-dehydrogenase, long-chain mannitol-1-phosphate dehydrogenase, M1PDH, M1PDH1, M1PDH2, M1PDH3, mannitol 1-phosphate 5-dehydrogenase, mannitol 1-phosphate dehydrogenase, mannitol-1-phosphate dehydrogenase, MPD, MpdA, MPDH, MPDH1, MPDH2, MPDH3, Mtl-1-P dehydrogenase, MtlD, NAD+-dependent mannitol-1-phosphate dehydrogenase, NADH-dependent mannitol-1-phosphate 5-dehydrogenase
ECTree
1.1.1.17 mannitol-1-phosphate 5-dehydrogenaseAdvanced search results
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Engineering
Engineering on EC 1.1.1.17 - mannitol-1-phosphate 5-dehydrogenase
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ENGINEERING 
ORGANISM
UNIPROT
COMMENTARY 
LITERATURE
additional information
additional information
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construction of a disruption mutant, that shows elevated levels of trehalose, but is viable, and the conidia germinate normally, the mutant is less pathogenic in infected tobacco plants compared to the wild-type fungus, overview
additional information
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construction of a disruption mutant, that shows elevated levels of trehalose, but is viable, and the conidia germinate normally, the mutant is less pathogenic in infected tobacco plants compared to the wild-type fungus, overview
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additional information
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gene disruption mutant, reduced growth on glucitol, no growth on mannitol as sole carbon source
additional information
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mannitol accumulation in mtlD transgenics is expected to confer a range of biotic and abiotic-stress tolerance, phenotypes, overview
additional information
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C-terminal truncation, lacking 162 amino acids of the C-terminus, 10% in vivo activity compared to the wild-type form
additional information
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the enzyme competes with two sorbitol-6-phosphate dehydrogenase for D-fructose 6-phosphate, a mutant strain deficient for both L- and D-lactate dehydrogenase activities shows two highly active sorbitol-6-phosphate dehydrogenase genes srlD1 and srlD2, that are constitutively expressed at a high level in this mutant, the mannitol production of the mutant strain is reduced compared to the wild-type, overview
Information
