1.1.1.168: 2-dehydropantolactone reductase (Re-specific)

This is an abbreviated version, for detailed information about 2-dehydropantolactone reductase (Re-specific), go to the full flat file.

Reaction

(R)-pantolactone
+
NADP+
=
2-dehydropantolactone
+
NADPH
+
H+

Synonyms

(R)-pantoyl-lactone:NADP+ oxidoreductase (A-specific), 2-dehydropantoyl-lactone reductase, 2-dehydropantoyl-lactone reductase (A-specific), 2-ketopantoyl lactone reductase, ketopantoyl lactone reductase, reductase, 2-oxopantoyl lactone

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.168 2-dehydropantolactone reductase (Re-specific)

Systematic Name

Systematic Name on EC 1.1.1.168 - 2-dehydropantolactone reductase (Re-specific)

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SYSTEMATIC NAME
IUBMB Comments
(R)-pantolactone:NADP+ oxidoreductase (Re-specific)
The yeast enzyme differs from that from Escherichia coli [EC 1.1.1.214 2-dehydropantolactone reductase (Si-specific)], which is specific for the Si-face of NADP+, and in receptor requirements from EC 1.1.99.26 3-hydroxycyclohexanone dehydrogenase.