1.1.1.166: hydroxycyclohexanecarboxylate dehydrogenase

This is an abbreviated version, for detailed information about hydroxycyclohexanecarboxylate dehydrogenase, go to the full flat file.

Reaction

(1S,3R,4S)-3,4-Dihydroxycyclohexane-1-carboxylate
+
NAD+
=
(1S,4S)-4-hydroxy-3-oxocyclohexane-1-carboxylate
+
NADH
+
H+

Synonyms

(-)t-3,t-4-dihydroxycyclohexane-c-1-carboxylate-NAD oxidoreductase, dihydroxycyclohexanecarboxylate dehydrogenase

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.166 hydroxycyclohexanecarboxylate dehydrogenase

Systematic Name

Systematic Name on EC 1.1.1.166 - hydroxycyclohexanecarboxylate dehydrogenase

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SYSTEMATIC NAME
IUBMB Comments
(1S,3R,4S)-3,4-dihydroxycyclohexane-1-carboxylate:NAD+ 3-oxidoreductase
Acts on hydroxycyclohexanecarboxylates that have an equatorial carboxy group at C-1, an axial hydroxy group at C-3 and an equatorial hydroxy or carbonyl group at C-4, including (-)-quinate and (-)-shikimate.