1.1.1.159: 7alpha-hydroxysteroid dehydrogenase
This is an abbreviated version!
For detailed information about 7alpha-hydroxysteroid dehydrogenase, go to the full flat file.
Word Map on EC 1.1.1.159
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1.1.1.159
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chenodeoxycholic
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cholic
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testosteroni
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bacteroides
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thin-layer
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3alpha-hydroxysteroid
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synthesis
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fragilis
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7alpha-oh
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glycochenodeoxycholic
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nadp-dependent
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ursodeoxycholic
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perfringens
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degradation
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analysis
- 1.1.1.159
-
chenodeoxycholic
-
cholic
- testosteroni
- bacteroides
-
thin-layer
-
3alpha-hydroxysteroid
- synthesis
- fragilis
-
7alpha-oh
-
glycochenodeoxycholic
-
nadp-dependent
-
ursodeoxycholic
- perfringens
- degradation
- analysis
Reaction
Synonyms
7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid, J-1-1, NADP(H)-dependent 7alpha-HSDH, NADP(H)-dependent 7alpha-hydroxysteroid dehydrogenase, NADP+-dependent 7alpha-HSDH, nicotinamide adenine dinucleotide phosphate-dependent 7alpha-hydroxysteroid dehydrogenase
ECTree
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Temperature Stability
Temperature Stability on EC 1.1.1.159 - 7alpha-hydroxysteroid dehydrogenase
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15 - 65
the relative activity of the free enzyme drastically decreases at temperatures over 35°C, with minimal activity observed at 45°C. In contrast, the immobilized preparations are relatively stable at temperatures ranging from 15 to 35°C, with the relative activities of enzyme immobilized on the amino-epoxy resin and epoxy resin at 56.4% and 61.0%, respectively, after 2 h at 65°C
4 - 37
purified recombinant enzyme, no change in activity after incubation at 4°C or 25°C for 108 h, but dramatic decrease in activity at 37°C
40
65
40
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73% of the enzyme activity is maintained after heat treatment at 40°C for 100 h