1.1.1.159: 7alpha-hydroxysteroid dehydrogenase

This is an abbreviated version, for detailed information about 7alpha-hydroxysteroid dehydrogenase, go to the full flat file.

Reaction

Synonyms

7-alpha-HSDH, 7-HSDH, 7alpha-HSD, 7alpha-HSDH, 7alpha-hydroxy steroid dehydrogenase, 7alpha-hydroxysteroid dehydrogenase, Bile acid-inducible protein, CA 7alpha-HSDH, Ca7alpha-HSDH, dehydrogenase, 7alpha-hydroxy steroid

ECTree

     1 Oxidoreductases

         1.1 Acting on the CH-OH group of donors

             1.1.1 With NAD⁺ or NADP⁺ as acceptor

                1.1.1.159 7alpha-hydroxysteroid dehydrogenase

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Results

in table

9

Activating Compound

639

AA Sequence

8

Application

1

CAS Registry Number

9

Cloned(Commentary)

28

Cofactor

3

Crystallization (Commentary)

16

Engineering

12

General Information

3

General Stability

35

Inhibitors

3

KCat/KM [mM/s]

51

KM Value [mM]

9

Metals/Ions

15

Molecular Weight [Da]

19

Natural Substrates/ Products (Substrates)

45

Organism

3

Pathway

14

PDB ID

15

pH Optimum

3

pH Range

3

pH Stability

13

Purification (Commentary)

4

Reaction

3

Reaction Type

39

Reference by Title

2

Source Tissue

27

Specific Activity [micromol/min/mg]

2

Storage Stability

121

Substrates and Products (Substrate)

11

Subunits

26

Synonyms

1

Systematic Name

3

Temperature Optimum [°C]

1

Temperature Range [°C]

13

Temperature Stability [°C]

14

Turnover Number [1/s]

Organism

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Organism on EC 1.1.1.159 - 7alpha-hydroxysteroid dehydrogenase

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ORGANISM

COMMENTARY

LITERATURE

UNIPROT

SEQUENCE DB

SOURCE

Acinetobacter calcoaceticus

-

740787

-

-

brenda

Acinetobacter lwoffii

-

701240

-

-

brenda

Bacteroides fragilis

4 entries

Bacteroides fragilis NCTC 9343

ATCC25285

697994

-

-

brenda

Bacteroides intestinalis

AM-1

697994

-

-

brenda

Bacteroides intestinalis am-1

AM-1

697994

-

-

brenda

Brevibacterium fuscum

-

286075

-

-

brenda

Clostridium sardiniense

2 entries

Clostridium scindens

formerly Eubacterium sp. strain VP1

655302

-

-

brenda

Comamonas testosteroni

i.e. Pseudomonas testosteroni

740971

S5U393

UniProt

brenda

Comamonas testosteroni ATCC 11996

i.e. Pseudomonas testosteroni

740971

S5U393

UniProt

brenda

Escherichia coli

3 entries

Escherichia coli HB101

-

697994

-

-

brenda

Eubacterium sp.

strain VPI 12708

286082

-

-

brenda

Eubacterium sp. VPI 12708

strain VPI 12708

286082

-

-

brenda

Paeniclostridium sordellii

2 entries

Pseudomonas sp.

2 entries

Pseudomonas sp. B-0831

strain B-0831

656301

-

-

brenda

Stenotrophomonas maltophilia

2 entries

Stenotrophomonas maltophilia CBS 897.97

strain CBS 897.97

670898

-

-

brenda

Bacteroides fragilis

-

286078, 286079, 740787

-

-

brenda

Bacteroides fragilis

ATCC25285

697994

-

-

brenda

Bacteroides fragilis

strain ATCC 25285

655302

Q9S3U5

SwissProt

brenda

Bacteroides fragilis

strain ATCC 25285

670926

-

-

brenda

Clostridium sardiniense

-

286076

-

-

brenda

Clostridium sardiniense

-

740787, 741371

G9FRD7

UniProt

brenda

Escherichia coli

-

286072, 286073, 286074, 286077, 286080, 286083, 740787

-

-

brenda

Escherichia coli

-

286081

P0AET8

Uniprot

brenda

Escherichia coli

strain HB101

286085, 655302

-

-

brenda

Paeniclostridium sordellii

-

286084

-

-

brenda

Paeniclostridium sordellii

strain ATCC 9714

655302

-

-

brenda

Pseudomonas sp.

-

740787

-

-

brenda

Pseudomonas sp.

strain B-0831

656301

-

-

brenda

Stenotrophomonas maltophilia

-

740787

-

-

brenda

Stenotrophomonas maltophilia

strain CBS 897.97

670898

-

-

brenda

Show Organism (29 entries)