1.1.1.157: 3-hydroxybutyryl-CoA dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxybutyryl-CoA dehydrogenase, go to the full flat file.

Reaction

(S)-3-hydroxybutanoyl-CoA
+
NADP+
=
3-acetoacetyl-CoA
+
NADPH
+
H+

Synonyms

(S)-3-hydroxybutyryl-CoA dehydrogenase, beta-hydroxybutyryl coenzyme A dehydrogenase, beta-hydroxybutyryl-CoA dehydrogenase, BHBD, CP 26, dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate), L(+)-3-hydroxybutyryl-CoA dehydrogenase, L-(+)-3-hydroxybutyryl-CoA dehydrogenase, Msed_0399

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase

pH Optimum

pH Optimum on EC 1.1.1.157 - 3-hydroxybutyryl-CoA dehydrogenase

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pH OPTIMUM
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
9.5
-
at the pH optimum 6.5 the reduction of 3-acetoacetyl-CoA is 14times faster than the oxidation of (S)-3-hydroxybutanoyl-CoA at its pH optimum 9.5