1.1.1.157: 3-hydroxybutyryl-CoA dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxybutyryl-CoA dehydrogenase, go to the full flat file.

Reaction

(S)-3-hydroxybutanoyl-CoA
+
NADP+
=
3-acetoacetyl-CoA
+
NADPH
+
H+

Synonyms

(S)-3-hydroxybutyryl-CoA dehydrogenase, beta-hydroxybutyryl coenzyme A dehydrogenase, beta-hydroxybutyryl-CoA dehydrogenase, BHBD, CP 26, dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate), L(+)-3-hydroxybutyryl-CoA dehydrogenase, L-(+)-3-hydroxybutyryl-CoA dehydrogenase, Msed_0399

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase

Reference

Reference on EC 1.1.1.157 - 3-hydroxybutyryl-CoA dehydrogenase

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REF.
AUTHORS
TITLE
JOURNAL
VOL.
PAGES
YEAR
ORGANISM (UNIPROT)
PUBMED ID
SOURCE
Hartmanis, M.G.N.; Sliwkowski, M.X.
Selenomethionine-containing thiolase and 3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri
Curr. Top. Cell. Regul.
27
479-486
1985
Clostridium kluyveri
Manually annotated by BRENDA team
Sliwkowski, M.X.; Hartmanis, M.G.N.
Simultaneous single-step purification of thiolase and NADP-dependent 3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri
Anal. Biochem.
141
344-347
1984
Clostridium kluyveri
Manually annotated by BRENDA team
Madan, V.K.; Hillmer, P.; Gottschalk, G.
Purification and properties of NADP-dependent L(+)-3-hydroxybutyryl-CoA dehydrogenase from Clostridium kluyveri
Eur. J. Biochem.
32
51-56
1973
Clostridium kluyveri
Manually annotated by BRENDA team
Hawkins, A.B.; Adams, M.W.; Kelly, R.M.
Conversion of 4-hydroxybutyrate to acetyl coenzyme A and its anapleurosis in the Metallosphaera sedula 3-hydroxypropionate/4-hydroxybutyrate carbon fixation pathway
Appl. Environ. Microbiol.
80
2536-2545
2014
Metallosphaera sedula (A4YDS4), Metallosphaera sedula DSM 5348 (A4YDS4)
Manually annotated by BRENDA team