1.1.1.157: 3-hydroxybutyryl-CoA dehydrogenase

This is an abbreviated version, for detailed information about 3-hydroxybutyryl-CoA dehydrogenase, go to the full flat file.

Reaction

(S)-3-hydroxybutanoyl-CoA
+
NADP+
=
3-acetoacetyl-CoA
+
NADPH
+
H+

Synonyms

(S)-3-hydroxybutyryl-CoA dehydrogenase, beta-hydroxybutyryl coenzyme A dehydrogenase, beta-hydroxybutyryl-CoA dehydrogenase, BHBD, CP 26, dehydrogenase, L-3-hydroxybutyryl coenzyme A (nicotinamide adenine dinucleotide phosphate), L(+)-3-hydroxybutyryl-CoA dehydrogenase, L-(+)-3-hydroxybutyryl-CoA dehydrogenase, Msed_0399

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.157 3-hydroxybutyryl-CoA dehydrogenase

Inhibitors

Inhibitors on EC 1.1.1.157 - 3-hydroxybutyryl-CoA dehydrogenase

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INHIBITORS
ORGANISM
UNIPROT
COMMENTARY hide
LITERATURE
IMAGE
5,5'-dithiobis(2-nitrobenzoic acid)
-
0.05 mM, 80% inhibition
iodoacetamide
-
1 mM, slight inhibition
N-ethylmaleimide
-
1 mM, slight inhibition
p-chloromercuribenzoate
-
1 mM, complete inhibition