1.1.1.156: glycerol 2-dehydrogenase (NADP+)

This is an abbreviated version, for detailed information about glycerol 2-dehydrogenase (NADP+), go to the full flat file.

Reaction

glycerol
+
NADP+
=
Glycerone
+
NADPH
+
H+

Synonyms

DHA oxidoreductase, DHAR, dihydroxy (reduced nicotinamide adenine dinucleotide phosphate) reductase, dihydroxyacetone reductase, dihydroxyacetone reductase (NADPH), GDH4, GLD2, glycerol:NADP 2-oxidoreductase, dihydroxyacetone forming, NADP-dependent GLDH, NADPH-DHAR

ECTree

     1 Oxidoreductases
         1.1 Acting on the CH-OH group of donors
             1.1.1 With NAD+ or NADP+ as acceptor
                1.1.1.156 glycerol 2-dehydrogenase (NADP+)

Substrates Products

Substrates Products on EC 1.1.1.156 - glycerol 2-dehydrogenase (NADP+)

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SUBSTRATE
PRODUCT                       
REACTION DIAGRAM
ORGANISM
UNIPROT
COMMENTARY
(Substrate) hide
LITERATURE
(Substrate)
COMMENTARY
(Product) hide
LITERATURE
(Product)
Reversibility
r=reversible
ir=irreversible
?=not specified
1,2,3-butanetriol + NADP+
1,3-dihydroxybutan-2-one + NADPH
show the reaction diagram
-
18% of the activity compared to glycerol
-
?
1,2-butanediol + NADP+
1-hydroxybutan-2-one + NADPH
show the reaction diagram
-
19% of the activity compared to glycerol
-
?
1,2-ethanediol + NADP+
hydroxyacetaldehyde + NADPH
show the reaction diagram
-
0.3% of the activity compared to glycerol
-
r
1,2-propanediol + NADP+
hydroxyacetone + NADPH
show the reaction diagram
2,3-butanediol + NADP+
3-hydroxybutan-2-one + NADPH
show the reaction diagram
dihydroxyacetone + NADH + H+
glycerol + NAD+
show the reaction diagram
dihydroxyacetone + NADPH + H+
glycerol + NADP
show the reaction diagram
-
-
-
ir
dihydroxyacetone + NADPH + H+
glycerol + NADP+
show the reaction diagram
dihydroxyacetonephosphate + NADPH
glycerol 3-phosphate + NADP+
show the reaction diagram
glycerol + NADP+
dihydroxyacetone + NADPH
show the reaction diagram
iso-erythritol + NADP+
? + NADPH
show the reaction diagram
-
0.9% of the activity compared to glycerol
-
r
L-arabitol + NADP+
? + NADPH
show the reaction diagram
-
11% of the activity compared to glycerol
-
?
L-glyceraldehyde + NADPH
L-glycerol + NADP+
show the reaction diagram
L-ribulose + NADPH
? + NADP+
show the reaction diagram
-
very low activity
-
?
meso-erythritol + NADP+
? + NADPH
show the reaction diagram
methylglyoxal + NADPH
2-hydroxypropanal + NADP+
show the reaction diagram
-
very low activity
-
?
propan-2-ol + NADP+
acetone + NADPH
show the reaction diagram
-
very low activity
-
?
pyruvaldehyde + NADPH
lactaldehyde + NADP+
show the reaction diagram
-
very low activity
-
?
sedoheptulose + NADPH
? + NADP+
show the reaction diagram
-
very low activity
-
?